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About the Role

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Scientist to join the Analytical and Biological Mass Spectrometry Group (ABMS). In this role, you will work in an innovative mass spectrometry lab and execute LC-MS methods for characterizing biotherapeutic products to support all stages of drug development, from early-stage candidate selection to late-stage regulatory submissions. You will develop innovative analytical technologies to support Regeneron’s diverse R&D pipeline. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Responsibilities

Execute established protocols and clearly communicate analytical characterization of biotherapeutics, including monoclonal antibodies, Fc-fusion proteins, and other modalities (antibody-drug conjugates, antibody-oligonucleotide conjugates, adeno-associated virus, siRNA, etc.), to support drug development
Execute characterization activities, with an emphasis on intact-mass LC-MS technique, to elucidate critical quality attributes such as charge variants, size variants, and post-translational modifications
Provide analytical support for cross-functional teams, including formulation development, upstream/downstream process development, and manufacturing, to solve drug development challenges
Independently conduct sample preparation and LC-MS analyses in compliance with SOPs, and document experimental procedures and results in electronic laboratory notebook (ELN)
Present data at group and project meetings; write technical reports, SOPs, and regulatory filing reports, etc.
Develop LC-MS based analytical methods to support various R&D programs
Use strong organization and communication to plan and prioritize work, manage and visualize data, and deliver clear, timely updates
Thrive in a fast-paced, collaborative environment, consistently delivering results with efficiency and ownership
Quickly learn new technologies, solve complex problems, and demonstrate strong passion for science and innovation
Be self-motivated and proactive, with the ability to prioritize effectively and drive work forward with minimal supervision

Requirements

Bachelor’s or Master’s degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field
Industrial or academic experience in LC-MS based analytical characterization of protein therapeutics
Hands-on experience with advanced mass spectrometers, liquid chromatography, various separation technologies, and data processing software is desired
Experience with intact mass analysis is a plus

Skills

LC-MS based analysis of biotherapeutics
Monoclonal antibodies
Fc-fusion proteins
Antibody-drug conjugates
Antibody-oligonucleotide conjugates
Adeno-associated virus
siRNA
Advanced mass spectrometers
Liquid chromatography
Various separation technologies
Data processing software
Intact mass analysis
Organization
Communication
Data management
Data visualization

Location

Tarrytown, NY

Work Type

Full-time
On-site

Education Level

Bachelor’s degree
Master’s degree

Salary/Compensations

$93,900.00 - $153,300.00

Benefits

Annual bonuses or other incentive plans
Equity awards
Pension or retirement benefits
401(k) company match
Health and wellness programs
Fitness centers
Insurance benefits (e.g. medical, dental, vision, life and disability)
Paid time off
Family support benefits

About the Company

Regeneron uses science and innovation to develop life-changing medicines for people with serious diseases.
We are committed to building a workplace with an inclusive culture.
Regeneron offers a competitive and comprehensive total rewards package.

Equal Opportunity

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.
Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.