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About the Role

Join the Quantitative Bioanalytics (QBA) team within the Analytical and Biological Mass Spectrometry (ABMS) Group at Regeneron. This role involves developing, qualifying, and applying LC-MS-based bioanalytical assays and other analytical methods in a state-of-the-art mass spectrometry laboratory to support R&D programs. You will contribute to innovative mass spectrometry technologies for bioanalysis and biologics characterization across Regeneron’s therapeutic pipeline.

Responsibilities

Perform LC-MS-based assay development, qualification, and validation for biotherapeutics and biomarkers in biological matrices.
Provide bioanalytical support for research, preclinical, clinical, and biodistribution studies by quantifying therapeutics or biomarkers in biological study samples.
Apply state-of-the-art LC-MS platforms coupled with manual or automated sample preparation to investigate various biotherapeutics and novel modalities.
Troubleshoot and optimize methods, ensuring data quality and scientific integrity.
Maintain accurate records, including electronic lab notebooks (ELNs), and analyze/interpret results.
Communicate findings effectively at team and cross-functional meetings, and in technical reports, regulatory documents, conferences, and publications.
Develop and troubleshoot analytical methods, solve scientific and technical problems, and explore new technologies.
Demonstrate excellent attention to detail, good record keeping, and organizational skills.
Work independently and collaboratively across teams, coordinating samples, activities, priorities, timelines, and deliverables.
Adapt to changing priorities and think/act independently on well-defined projects.
Communicate clearly and effectively, with excellent verbal and written communication skills.
Be results-driven, adaptable, and scientifically curious in an innovative, fast-paced R&D environment.

Requirements

BS or MS in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field.
6+ years (MS) or 8+ years (BS) of industrial or academic experience with LC-MS based bioanalytical assays for biomarkers, protein therapeutics, antibodies, AAVs, or other therapeutic modalities.
Hands-on experience with LC-MS and advanced mass spectrometry platforms (triple quadrupole, Q-TOF, and Orbitrap).
Strong understanding of mass spectrometry techniques and their applications to large-molecule analysis.
Experience with GxP laboratory environment, documentation, and regulatory compliance is a plus.
Deep understanding of analytical method qualification and validation is highly desired.
Knowledge of ELISA and other ligand-binding assays is a plus.

Skills

LC-MS
Mass Spectrometry
Assay Development
Assay Qualification
Assay Validation
Bioanalysis
Biologics Characterization
Triple Quadrupole
Q-TOF
Orbitrap
Sample Preparation
Method Troubleshooting
Method Optimization
Data Analysis
Data Interpretation
Record Keeping
Electronic Lab Notebooks (ELNs)
Communication Skills
Attention to Detail
Organizational Skills
Teamwork
Adaptability
Scientific Curiosity

Location

Tarrytown, NY

Work Type

Full-time
On-site

Experience Level

6+ years (MS) or 8+ years (BS) of industrial or academic experience

Education Level

BS or MS in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field

Salary/Compensations

$93,900.00 - $153,300.00

Benefits

Annual bonuses or other incentive plans
Equity awards
Pension or retirement benefits
401(k) company match
Health and wellness programs
Fitness centers
Insurance benefits (e.g. medical, dental, vision, life and disability)
Paid time off
Family support benefits

About the Company

Regeneron uses science and innovation to develop life-changing medicines for people with serious diseases.
We are committed to building a workplace with an inclusive culture.
We believe we do our best work when we are together.

Equal Opportunity

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.
Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.