PhD Candidate - Immunogenomics of Arthritic Joint Disease
Garvan Institute of Medical Research · AU
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About the Role
This PhD position focuses on the immunogenomics of arthritic joint disease, utilizing advanced genomic technologies and analytical pipelines at the Broad Institute of MIT and Harvard. The research will leverage the Arthritis Tissue Biobank at Garvan Institute to gain insights into disease mechanisms, treatment resistance, and novel drug targets, directly contributing to the development of new arthritis therapies.
Responsibilities
- Apply genomic technologies and analytical pipelines uniquely available at Broad Institute.
- Analyse the world's first single-cell, long-read sequencing dataset integrating transcriptome, clonotypes, isoforms and acquired mutations directly within diseased arthritic joints.
- Access and analyse other unique datasets, including large-scale single-cell genetics analyses of hundreds of patients.
- Generate insights into disease mechanisms, treatment resistance, and novel drug targets.
- Contribute insights to the established pipeline for producing and pre-clinically testing novel arthritis therapies.
Requirements
- Must be a domestic candidate.
- Applications must include CV, transcripts, and a thoughtful, detailed, and original cover letter.
Skills
- Genomic technologies
- Analytical pipelines
- Single-cell sequencing
- Long-read sequencing
- Transcriptome analysis
- Clonotype analysis
- Isoform analysis
- Mutation analysis
- Genetics analysis
Location
- Cambridge, MA, USA (Broad Institute)
- Australia (Garvan Institute)
Work Type
- Full-time
- PhD Candidate
Experience Level
- PhD Candidate
Education Level
- PhD
Salary/Compensations
- $39,991 per annum (2027 rate) stipend for 3.5 years
- $25,000 Global Mobility Grant (one-off)
About the Company
- The Garvan Institute is involved in arthritis research.
- The Broad Institute of MIT and Harvard offers unique genomic technologies and analytical pipelines.