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About the Role

The Head of Oncology Medical Affairs Business Operations leads day-to-day business operations, planning, governance, resource management, communications, and organizational enablement for the Oncology Medical Affairs organization. This role partners across multiple functions to translate priorities into coordinated execution, strengthening leadership team effectiveness and enabling measurable impact for patients.

Responsibilities

Lead day-to-day business operations for the Chief Oncology Medical Officer, including prioritization and coordination of key interactions, meetings, presentations, deliverables, and organizational commitments.
Anticipate operational needs, surface risks and dependencies, and ensure timely follow-through on decisions and actions.
Lead annual, semester, and longer-range business planning for Oncology Medical Affairs, including development, alignment, implementation, and tracking of organizational goals, success measures, and execution plans.
Provide clear visibility to progress, risks, interdependencies, and required decisions.
Lead the operating rhythm for OMALT, including agendas, strategic reviews, offsites, decision governance, action tracking, and accountability mechanisms.
Continuously improve leadership team processes to focus time on the highest-value priorities and strengthen collaboration and execution.
Lead or coordinate high-priority business and organizational initiatives on behalf of the Chief Oncology Medical Officer.
Build strong partnerships across global, regional, and country Medical Affairs and with Oncology, Research, Development, Commercial, People Experience, Finance, Communications, and other enabling functions to align stakeholders and deliver outcomes.
Coordinate resource and full-time equivalent (FTE) planning across Oncology Medical Affairs, helping leaders assess capacity, capabilities, trade-offs, and deployment against strategic priorities.
Maintain visibility to resource needs and support disciplined prioritization and organizational decision-making.
Partner with People Experience and leaders to advance workforce and talent planning, succession, leadership development, colleague engagement, onboarding, leadership transitions, and organizational effectiveness.
Help foster a culture of inclusion, accountability, collaboration, innovation, and continuous improvement.
Develop a strong understanding of Pfizer Oncology strategy, Medical Affairs priorities, evidence-generation activities, and organizational capabilities.
Partner with Communications to develop executive presentations, briefing materials, talking points, town halls, organizational updates, site visits, and other internal and external engagements that strengthen clarity, alignment, and confidence.
Understand, embrace, and regularly use artificial intelligence (AI), digital tools, and advanced analytics to improve planning, insight generation, communications, decision support, and operational efficiency.
Promote responsible adoption of AI-enabled ways of working in alignment with Pfizer policies and applicable requirements, while identifying opportunities to simplify processes and improve organizational impact.

Requirements

Bachelor's degree with 12+ years of relevant experience; or master's degree, MBA, MPH, PharmD, or equivalent with 10+ years of relevant experience; or PhD with 7+ years of relevant experience.
Relevant experience in the biopharmaceutical industry, healthcare, Medical Affairs, R&D operations, business operations, strategy, or a related field.
Demonstrated experience leading complex, cross-functional initiatives and delivering results in a global, highly matrixed organization.
Strong business planning, operational leadership, project and portfolio management, organizational effectiveness, and stakeholder management capabilities.
Exceptional written, verbal, presentation, and executive communication skills, with the judgment and discretion required to work with senior leaders and sensitive information.
Proven ability to influence without direct authority, manage competing priorities, and convert ambiguous or complex objectives into clear plans, decisions, and measurable outcomes.
Demonstrated proficiency using AI and digital productivity tools regularly and responsibly to improve the quality, speed, and effectiveness of work.
Oncology or Medical Affairs experience and an understanding of evidence generation, scientific communications, patient-centered medical strategy, and the healthcare ecosystem.
Experience in a Business Operations, Development Business Operations (DBO), strategy, program leadership, or organizational effectiveness role supporting a senior executive or leadership team.
Experience with FTE planning, workforce capacity management, resource allocation, and organizational prioritization.
Experience leading organizational change, business transformation, capability building, or leadership team effectiveness initiatives.
Demonstrated ability to apply AI, advanced analytics, and digital tools to business operations, decision support, communications, or process improvement.
Experience leading and developing colleagues or teams, including resources operating through matrix relationships.
Strong business acumen, executive presence, sound judgment, organizational maturity, and the ability to build trusted relationships across internal and external stakeholders.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship is not available for this role now or in the future.

Skills

Business operations
Planning
Governance
Resource management
Communications
Organizational enablement
Business acumen
Operational leadership
Cross-functional integration
Project management
Portfolio management
Stakeholder management
Executive communication
AI and digital tools proficiency
Oncology
Medical Affairs
Evidence generation
Scientific communications
Patient-centered medical strategy
Healthcare ecosystem
FTE planning
Workforce capacity management
Resource allocation
Organizational prioritization
Organizational change
Business transformation
Capability building
Leadership team effectiveness
Advanced analytics
Business operations
Decision support
Process improvement
Team leadership
Executive presence
Judgment
Organizational maturity
Relationship building

Location

Multiple locations

Work Type

Full-time

Experience Level

12+ years of relevant experience with Bachelor's degree
10+ years of relevant experience with Master's degree, MBA, MPH, PharmD, or equivalent
7+ years of relevant experience with PhD

Education Level

Bachelor's degree
Master's degree
MBA
MPH
PharmD
PhD

Salary/Compensations

$214,900.00 - $358,100.00
Eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary
Eligible to participate in our share based long term incentive program

Benefits

Comprehensive and generous benefits and programs
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation, holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Relocation assistance may be available

About the Company

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.
Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.
Pfizer is an E-Verify employer.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users.

Equal Opportunity

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.
Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.
Pfizer is an E-Verify employer.
This position requires permanent work authorization in the United States.