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About the Role
This role offers a unique opportunity to join a talented team focused on solving critical challenges in molecular data storage. The Research Associate will support reagent development, characterization, QC, assay development, on-chip DNA synthesis, and downstream sample processing. This is a full-time bench position requiring close collaboration with a supervisor and team members to support experiment planning and execution. We seek a trainable candidate with a strong work ethic, eager to learn and grow.
Responsibilities
- Support and contribute towards the research and development of a custom high-throughput DNA synthesis platform for DNA data storage.
- Operate, maintain, and troubleshoot custom DNA synthesizers.
- Prepare and QC stock reagents and buffers for enzymatic DNA synthesis, using pH and assay-specific readouts.
- Operate analytical tools for assessment of quality of oligonucleotides, including HPLC, LCMS, and capillary electrophoresis.
- Perform NGS library prep on sample DNA oligo pools.
- Optimize biochemical or related enzyme activity assays.
- Utilize lab management and data analysis software to document data and produce scientific presentations and reports on experimental findings.
- Strictly adhere to Standard Operating Procedures (SOPs) and documentation standards for data integrity.
- Maintain clear written and verbal communication with your supervisor and cross-functional teams to ensure alignment on project timelines.
Requirements
- Bachelor's degree in Biochemistry, Chemistry, Molecular Biology, Biotechnology, or a closely related field.
- Experience executing and troubleshooting biochemistry and molecular biology protocols in a research laboratory environment.
- Must be a creative and detail-oriented person with excellent analytical, verbal, and written communication skills.
- Exceptional collaboration skills and ability to work seamlessly in a dynamic and fast-paced environment.
- Must be able to move about the laboratory and office environment regularly, including standing and walking for extended periods (up to 6–8 hours per day).
- Must have fine motor skills and steady hands to handle delicate instruments, operate laboratory equipment, pipette accurately, and perform repetitive benchwork with precision.
- Must be able to lift and carry up to 40 pounds occasionally.
- Must have sufficient visual acuity to read small print on labels, instrument displays, and computer monitors, including close vision, color vision, and the ability to adjust focus.
- Must be able to communicate effectively in spoken and written English, including reading technical documents and participating in team meetings.
- Must be able to wear appropriate personal protective equipment (PPE) such as lab coats, gloves, and safety goggles as required.
- Requires frequent standing, sitting, and occasional bending or reaching over lab benches or into biosafety cabinets.
Skills
- Enzymatic DNA synthesis
- Reagent development
- Characterization
- Quality Control (QC)
- Biochemical assay development
- Enzyme assay development
- On-chip DNA synthesis
- Downstream sample processing
- NGS library prep
- Analysis
- HPLC
- LCMS
- Capillary electrophoresis
- Next Generation DNA sequencing (NGS)
- qPCR
- DNA hybridization methods
- Liquid handling laboratory automation
- Lab management software
- Data analysis software
- Scientific presentations
- Scientific reports
- Standard Operating Procedures (SOPs)
- Data integrity
- Written communication
- Verbal communication
Location
- South San Francisco
Work Type
- Full-time
- Onsite
Experience Level
- Master's degree or prior relevant industry experience is a plus
- Experience in a biotech or pharma R&D environment is highly desirable
Education Level
- Bachelor's degree in Biochemistry, Chemistry, Molecular Biology, Biotechnology, or a closely related field
Equal Opportunity
- Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.