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About the Role
Lime Therapeutics is seeking a highly motivated Research Associate – In Vivo Biology to join their growing biology team and advance their oncology drug development programs. This hands-on role is ideal for an early-career scientist passionate about experimental biology, eager to build new technical skills, and excited to make a meaningful contribution at an early-stage biotech company.
Responsibilities
- Conduct pivotal studies in relevant cancer models to evaluate the efficacy and tolerability of novel therapeutic candidates.
- Perform routine mouse handling, restraint, and compound administration by oral gavage and intraperitoneal (IP), subcutaneous (SC), and intravenous (IV) injection.
- Collect and process tissues for downstream molecular, biochemical, histological, and flow cytometry-based analyses.
- Establish and maintain mammalian cell cultures, including cancer cell lines, primary cells, and organoids, and support cell-based assays and molecular biology experiments.
- Keep accurate experimental records, analyze study data in GraphPad Prism and Excel, and clearly communicate results to the scientific team.
- Prepare experimental materials, maintain lab equipment and supplies, and ensure compliance with IACUC-approved protocols and lab safety standards.
- Work collaboratively in a fast-paced startup, adapt to evolving research priorities, and support time-sensitive experiments, including occasional evening or weekend work as animal study schedules require.
Requirements
- BS or MS in Biology or a related field.
- Hands-on rodent in vivo experience.
- Exposure to molecular assays in an academic, biotech, pharmaceutical, or CRO setting.
- Demonstrated proficiency in mouse handling, restraint, and dosing.
- Working knowledge of IACUC protocols and animal welfare standards.
- Strong aseptic technique and experience maintaining cancer cell lines and preparing cells for in vivo implantation.
- The discipline to follow protocols precisely and manage multiple concurrent studies.
- A drive to master new techniques and grow your skillset as programs advance.
- A self-starter who takes ownership and thrives in a high-accountability environment.
Skills
- In Vivo Biology
- Rodent handling
- Compound administration (oral gavage, IP, SC, IV)
- Tissue collection and processing
- Mammalian cell culture (cancer cell lines, primary cells, organoids)
- Cell-based assays
- Molecular biology experiments
- Data analysis (GraphPad Prism, Excel)
- IACUC protocols
- Aseptic technique
Location
- Manhattan, NY
Work Type
- Contract-to-hire
- Full-time
- In-person
Experience Level
- Early-career scientist
Education Level
- BS or MS in Biology or related field
Salary/Compensations
- $35–50/hour
Benefits
- Potential to convert to full-time
About the Company
- Lime Therapeutics is a venture-backed biotech startup pioneering therapies that target lipid-metabolic pathways in cancer, metabolic, and neurodegenerative diseases.
- Advancing novel therapeutic concepts toward IND-enabling studies and clinical development.
- The Ford Center Incubator is a vibrant hub for early-stage life science companies at The Rockefeller University.
Equal Opportunity
- Lime Therapeutics is an equal opportunity employer.