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About the Role
The Research Associate will be an integral member of the Vector Bioscience team, assisting in developing, characterizing, and producing AAV vectors. This role supports and collaborates with various research and development groups at our South San Francisco R&D laboratories.
Responsibilities
- Perform cell culture work, including thawing, maintaining, transfecting, and cryopreserving cell lines
- Production and purification of AAV vectors for various programs
- Collaborate with other teams to acquire and characterize vectors
- Document characterization of vectors and other activities
- Communicate results and timelines to other functional groups
- Collaborate in laboratory management and safety activities
Requirements
- Bachelor’s degree in a life science, chemical engineering or related discipline with 3+ years of experience or a Master’s degree with 1+ years of experience in cell culture and protein purification techniques
- Proven hands-on experience with sterile technique for handling and growing mammalian cell lines, including maintenance, cell characterization and differentiation, expansion, and banking
- Demonstrated experience with routine molecular biology techniques (cloning, DNA/RNA/protein isolation, digital PCR), plasmid preparation
- Protein expression and purification, and characterization
- Transfection and/or transformation experience with mammalian or bacterial cells
- Experience with purification and chromatography systems such as the AKTA
- Ability to work both independently and in a team-oriented environment to meet project goals and timelines
- Strong written and verbal communication skills
- Experience working with viruses, especially Adeno-Associated Virus (AAV)
- Industry experience
Skills
- Cell culture
- AAV vector production
- Vector characterization
- Molecular biology techniques
- Cloning
- DNA/RNA/protein isolation
- Digital PCR
- Plasmid preparation
- Protein expression
- Protein purification
- Transfection
- Transformation
- AKTA chromatography systems
- Sterile technique
- Mammalian cell line handling
- Written communication
- Verbal communication
Location
- South San Francisco, CA
Work Type
- On-site
- Laboratory-based
Experience Level
- 3+ years of experience with Bachelor's degree
- 1+ years of experience with Master's degree
Education Level
- Bachelor’s degree in a life science, chemical engineering or related discipline
- Master’s degree
Salary/Compensations
- $XXXXXX-XXXXXX
Benefits
- Medical, Dental and Vision Insurance
- Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long Term Incentive Plan for eligible positions
- Company fleet vehicle for eligible positions
- Referral bonus program
About the Company
- Astellas is a global life sciences company committed to turning innovative science into VALUE for patients.
- We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health.
- Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need.
- Values: Innovation, Integrity and Impact sit at the heart of what we do.
- Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
Equal Opportunity
- We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.