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About the Role
Isomorphic Labs is seeking a Senior Research Investigator specializing in biologics drug development to contribute to the pharmacology and translational biology strategy of novel large molecule therapeutics. This role involves harnessing cutting-edge AI drug design to accelerate scientific discovery and develop life-changing medicines.
Responsibilities
- Design, execute, and oversee comprehensive pharmacology plans for large molecule therapeutics.
- Lead the design and execution of in vivo efficacy and complex in vitro functional assays.
- Act as the Biology Lead for assigned projects, coordinating internal workflows and external CROs.
- Collaborate with computational biology and design teams to identify and evaluate new biologics projects.
- Partner closely with interdisciplinary teams to help build the generative AI platform and deploy cutting-edge tools.
Requirements
- PhD in Immunology, Cancer Biology, Molecular Biology, Biochemistry, Pharmacology or a related scientific discipline.
- 5+ years’ professional experience in an industry role within a biotech or pharma setting.
- Strong scientific expertise in disease models and their use in biologics drug development.
- Significant experience in the design and execution of studies for biologics drug discovery and development.
- Experience within the immunology, inflammation or oncology therapeutic areas.
- Proficiency with modalities such as multi-specifics or antibody drug conjugates (ADCs).
- Demonstrated proficiency in fostering and managing external collaborations with CROs and academic groups.
- Genuine passion and enthusiasm for applying AI/ML to drug design.
- Excellent communication (written and verbal) and interpersonal skills.
- Proven ability to work effectively in a cross-functional, collaborative team environment.
- Track record of creative problem solving in drug discovery.
- Strong growth mindset, adaptability, and eagerness to learn new concepts and techniques.
- Experience leveraging machine learning or computational biology techniques for biologics design and optimisation (Nice to have).
- Experience in antibody discovery, engineering, and optimisation strategies (Nice to have).
- In-depth understanding of protein structure-function relationships of antibodies (Nice to have).
Skills
- Pharmacology
- Translational Biology
- In Vivo & In Vitro Evaluation
- Drug Discovery
- Generative AI
- Machine Learning
- Computational Biology
- Immunology
- Cancer Biology
- Molecular Biology
- Biochemistry
- Antibody Drug Conjugates (ADCs)
- Multi-specifics
Location
- Remote
- Hybrid
Work Type
- Hybrid
Experience Level
- Senior
- 5+ years
Education Level
- PhD
About the Company
- Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.
- The company was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system.
- Their interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.
- They believe there is an underlying symmetry between biology and information science and harness AI to model complex biological phenomena.
- They have built a world-leading drug design engine comprising AI models capable of working across multiple therapeutic areas and drug modalities.
- They are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.
- They are getting closer to the promise of digital biology and achieving their ambitious mission to one day solve all disease with the help of AI.
Equal Opportunity
- We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law.
- If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.