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About the Role
We are looking for a Laboratory Research Scientist (LRS) to join the In Vivo Imaging team and play a vital role in supporting cutting-edge scientific research by ensuring the effective operation and maintenance of the nuclear imaging suite.
Responsibilities
- Perform in vivo and ex vivo imaging studies for Crick scientists and external collaborators using nuclear imaging technologies PET and SPECT
- Perform biodistribution studies with radio-labelled compounds
- Perform in-vivo irradiations using a SARRP irradiator
- Maintain and calibrate the PET-MRI and SPECT-CT scanners, HIDEX gamma counter, and SARRP irradiator including organising servicing
- Maintain and calibrate radioactive monitoring and counting equipment
- Ordering consumables and maintaining stocks of chemicals/reagents
- Assist with the development of standard operating procedures, health and safety compliance and maintaining and enforcing good laboratory practice
- Ensuring the imaging suite is safe and maintained in good working order working closely together with the radiation safety officer
- Administrative duties such as radioisotope logging and waste management
- Aid in general lab duties
- Perform PET and SPECT imaging and biodistribution studies
- Provide specialist technical and experimental support
- Contribute to the refinement and troubleshooting of imaging equipment and methodologies
- Manage the day-to-day operations of the facility, including equipment calibration and maintenance, laboratory organisation, database management and procurement of supplies
- Support data analysis and reporting
- Develop and maintain risk assessments and standard operating procedures (SOPs)
- Promote safe working practices
- Train and supervise colleagues in key techniques, protocols and equipment use
- Contribute to a supportive, innovative research environment through participation in group meetings, journal clubs, seminars and scientific discussions
Requirements
- BSc or equivalent experience in biomedical sciences, medical biology, veterinary medicine or related field
- Extensive experience in working with small animal models in a research setting
- Proven track record in pre-clinical nuclear imaging
- Experience in the use and maintenance of experimental pre-clinical nuclear imaging scanners (Mediso PET and SPECT)
- Experience in handling radioactive open sources
- Experience working in multidisciplinary research environments
- Ability to design imaging protocols tailored to specific research objectives
- Ability to collaborate effectively with internal and external partners
- Ability to plan own work activities independently
- Ability to set priorities and ensure effective service delivery
- Excellent organisational skills and record keeping
- Home Office personal licence (PIL A, B, C)
- Knowledge of regulatory frameworks for pre-clinical research, including the Animals (Scientific Procedures) Act 1986 and the 3Rs principles
- Excellent organisational skills
- Commitment to maintaining the highest ethical and scientific standards
Skills
- PET imaging
- SPECT imaging
- Biodistribution studies
- Radioisotope logging
- Waste management
- Equipment calibration
- Equipment maintenance
- Risk assessment development
- SOP development
- Safe working practices promotion
- Training and supervision
- Data analysis
- Reporting
- Database management
- Procurement
Location
- London, UK
Work Type
- Full-time
- Permanent
Experience Level
- Not specified
Education Level
- BSc or equivalent
Salary/Compensations
- From £37,735
Benefits
- 28 days of annual leave, plus three additional days over Christmas and bank holidays
- Defined contribution pension with employer contributions of up to 16%
- 24/7 GP consultation services
- Occupational health services and mental health support programs
- Eye care vouchers and discounted healthcare plans
- Back-up care for dependents
- Childcare support allowance
- Annual leave purchase options
- Crick Networks offering diverse groups’ support, community and inclusive social events
- Discounted gym memberships
- Bike-to-work scheme
- Shopping discounts
- Subsidised on-site restaurant and social spaces
About the Company
- The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.
- The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.
- The Biological Research Facility (BRF) at the Francis Crick Institute supports all animal research through a comprehensive animal care and use programme, providing high-quality laboratory animal resources, technical expertise, and in-vivo/ex-vivo research support. The BRF is committed to advancing animal welfare, improving scientific quality, supporting staff wellbeing, and maintaining transparency with stakeholders. Our multidisciplinary teams manage the husbandry of multiple species within state-of-the-art facilities, integrating innovative technologies and specialist skills.
- Within the BRF, the In Vivo Imaging (IVI) Facility offers a suite of cutting-edge multimodal imaging systems, including PET-MR, SPECT-CT, micro-CT, high-resolution ultrasound, optical imaging platforms, and a 9.4T MRI. These advanced technologies enable longitudinal, non-invasive imaging of biological processes in living tissues, supporting a diverse range of research areas from developmental biology to oncology, immunology, neuroscience, and regenerative medicine.
Equal Opportunity
- At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences.
- We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: weronika.kucala@crick.ac.uk.