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About the Role
The Principal Architect - Biopharma & Life Sciences (BLS) is the architectural leader and subject matter expert for complex pharmaceutical, biotechnology, advanced therapy, and life sciences projects. This role establishes project vision, design strategy, and architectural excellence across all project phases, acting as a trusted advisor to clients and teams to drive innovative, compliant, and high-performance facility solutions.
Responsibilities
- Serve as the architectural lead and technical authority for major BLS projects, providing strategic direction and oversight throughout the project lifecycle.
- Develop facility concepts, architectural design strategies, and planning solutions for pharmaceutical manufacturing, biotechnology, cell and gene therapy, laboratory, and research facilities.
- Lead client engagement activities, establishing trusted relationships and serving as the primary architectural advisor.
- Collaborate closely with engineering disciplines, project management, process architects, CQV teams, and construction personnel to deliver integrated design solutions.
- Guide multidisciplinary teams in resolving complex technical, operational, and regulatory challenges.
- Ensure designs comply with applicable building codes, GMP requirements, FDA regulations, ISO standards, biosafety requirements, and industry best practices.
- Lead architectural programming, space planning, workflow analysis, and facility master planning efforts.
- Direct development and quality review of design deliverables, including studies, reports, BIM models, drawings, specifications, and construction documentation.
- Conduct architectural reviews to ensure constructability, maintainability, operational efficiency, and lifecycle performance.
- Drive innovation in cleanroom design, laboratory environments, manufacturing suites, containment strategies, and controlled environments.
- Support project pursuit efforts, including proposal development, client presentations, technical interviews, and design narratives.
- Establish and maintain architectural standards, design guidelines, and best practices across the organization.
- Provide mentoring, coaching, and technical development support to architects, designers, and junior staff.
- Support risk management, change management, and technical decision-making processes during project execution.
- Participate in value engineering efforts while maintaining design intent, compliance, and project objectives.
- Contribute to thought leadership initiatives and represent Exyte at industry conferences, professional organizations, and client forums.
- Support global collaboration and knowledge sharing across Exyte offices and project teams.
Requirements
- Minimum 15+ years of architectural design experience.
- Minimum 10+ years of experience in pharmaceutical, biotechnology, advanced therapy, laboratory, or life sciences facility design.
- Demonstrated expertise designing complex GMP-regulated manufacturing facilities, laboratories, cleanrooms, and high-containment environments.
- Strong understanding of FDA, EMA, GMP, GxP, IBC, NFPA, and applicable life sciences industry standards.
- Proven leadership experience directing multidisciplinary design teams on large-scale projects.
- Advanced knowledge of architectural planning, facility programming, building systems integration, and BIM-enabled project delivery.
- Proficiency with Autodesk Revit, BIM 360/ACC, AutoCAD, and related design technologies.
- Experience supporting Design-Build, EPCM, and integrated project delivery approaches.
- Strong understanding of construction administration, project execution, and commissioning requirements.
- Experience leading technical reviews, design quality programs, and architectural governance processes.
- Demonstrated ability to manage multiple stakeholders, clients, and project priorities within fast-paced project environments.
- Excellent communication, presentation, and relationship management skills.
- Experience working in global teams and multi-office project execution environments preferred.
- Ability to travel as required to support project and client needs.
Skills
- Autodesk Revit
- BIM 360/ACC
- AutoCAD
Experience Level
- Principal
Education Level
- Bachelor's degree in Architecture required
- Master's degree in Architecture preferred
- Registered Architect (RA) required
- NCARB Certification strongly preferred
- LEED Accredited Professional, WELL AP, or similar credentials preferred
About the Company
- Exyte is a global leader in the design, engineering, and delivery of complex facilities for the life sciences and high-tech industries.