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About the Role
We are hiring a Scientist I to run hands-on cell and tissue culture work. You will process human tissue, build and maintain cell banks, run immunological assays, and turn bench work into robust, documented processes. This role is shared between Technical Operations and Science, involving partner study execution and system strengthening (SOPs, cell inventory, process consistency). It suits a scientist who enjoys bench work and has high standards for technical accuracy, precision, and data quality.
Responsibilities
- Process human lymphoid tissue and primary cells into single-cell suspensions and organoid cultures
- Apply donor acceptance criteria and track donor metadata to manage donor-to-donor variability
- Optimize and troubleshoot scientific protocols in a data-driven manner
- Execute partner study protocols on schedule under aseptic technique
- Cryopreserve, thaw, and recover primary human cells with consistent viability and yield
- Execute cell banking runs with full chain of custody from donor to vial
- Maintain the LN2 inventory: storage, sample tracking, and reconciliation
- Independently execute flow cytometry for immunophenotyping and study endpoint measurements
- Independently execute functional assays (e.g., ELISA, MSD, ELISpot, cytotoxicity), plus imaging or qPCR as programs require
- Analyze data (FlowJo, Prism, or equivalent) and contribute to study summaries for partners
- Clearly communicate data and findings to stakeholders
- Draft and revise SOPs, and help train new team members on them
- Support the move from research-grade documentation toward GLP-like rigor
- Maintain core equipment and reagent inventory, and support EH&S programs
Requirements
- PhD in immunology, cell biology, bioengineering, or a related field with 0–2 years of postdoctoral or industry experience; an MS with 5+ years of relevant industry experience; or a BS with 8+ years of relevant industry experience
- Hands-on proficiency in primary human cell or tissue culture under strict aseptic technique
- Hands-on proficiency in cryopreservation: freezing, thawing, and tracking cell stocks
- Hands-on proficiency in flow cytometry, plus at least one other immune assay method (e.g., ELISA, MSD, ELISpot, Luminex)
- Strong documentation habits grounded in data integrity (ALCOA+) principles: detailed electronic notebook entries, clear protocols, and records someone else can follow
- Collaboration across two teams and shifting between study execution and process work
- High standards for data quality and data integrity, and ability to apply scientific rigor to day-to-day operations
- Strong written and verbal skills, critical thinking and rational experimental design capabilities, and clear data presentation skills
- Ability to wear a tight-fitting respirator (e.g., N95 or half-face air-purifying respirator) when tasks require it
- Work with human-derived tissue and cells at BSL-2, including bloodborne pathogen training
- Ability to stand at the bench or biosafety cabinet for extended periods
- Ability to lift up to 25 lb (e.g., media cases and supplies)
Skills
- Cell and tissue culture
- Cell banking
- Immunological assays
- Aseptic technique
- Cryopreservation
- Flow cytometry
- ELISA
- MSD
- ELISpot
- Cytotoxicity
- Imaging
- qPCR
- FlowJo
- Prism
- SOP drafting
- Data integrity
- Written communication
- Verbal communication
- Critical thinking
- Experimental design
- Data presentation
Location
- Brisbane, CA
Work Type
- Fully onsite
- Occasional weekend work
Experience Level
- 0-2 years postdoctoral or industry experience (PhD)
- 5+ years relevant industry experience (MS)
- 8+ years relevant industry experience (BS)
Education Level
- PhD in immunology, cell biology, bioengineering, or a related field
- MS
- BS
Salary/Compensations
- $125k–140k USD base salary
Benefits
- Medical, dental, and vision coverage
- 401(k)
- Paid time off
- Equity
About the Company
- Drug discovery has a translation problem: more than 95% of drugs that succeed in animal models fail in humans.
- Building the alternative: human-first drug discovery, powered by organoids and AI, running on real human biology from the very first experiment.
- Platform is 87% concordant with clinical patient data - a vast improvement over the 3% translational success rate of animals.
- Demonstrated ability to model immunotoxicology, immunogen stimulation, and two autoimmune diseases.
- Numerous pharma partners including 3 Fortune 500 companies are already using the platform.
- Raised ~$30M from AIX Ventures, Marc Benioff, Jeff Dean, and Y Combinator.
- FDA Modernization Act 3.0 and the FDA's March 2026 validation framework provide regulatory tailwinds.
- Opportunity to build the first scaled engine for generating real human biological data and fundamentally change how medicines are discovered.
Equal Opportunity
- Parallel Bio is an equal opportunity employer committed to fostering an inclusive and respectful workplace.
- We encourage applications from individuals of all backgrounds, regardless of age, gender, ethnicity, religion, disability, or sexual orientation.