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About the Role
The Pharmaceutical Sciences Team Lead (PSTL) is a senior scientific and strategic leadership role responsible for advancing pharmaceutical development and CMC strategy across clinical and commercial-stage programs. This individual will lead cross-functional pharmaceutical sciences activities spanning formulation development, analytical development, process development, manufacturing, technology transfer, regulatory submissions, and lifecycle management. The role requires a proven leader with deep expertise in pharmaceutical development, strong regulatory and quality knowledge, and the ability to lead high-performing scientific teams in a fast-paced, matrixed environment. The PSTL will serve as a key contributor to corporate development strategy and represent Pharmaceutical Sciences in executive governance, regulatory interactions, and external partnerships.
Responsibilities
- Lead high-performing, collaborative, and accountable Pharmaceutical Sciences teams across multiple functional disciplines.
- Establish and drive organizational priorities, resource plans, and development goals aligned with corporate objectives.
- Identify program risks proactively and implement mitigation strategies to maintain timelines and deliverables.
- Provide scientific leadership for formulation development, analytical development, process development, manufacturing, and technology transfer.
- Partner with Non-clinical, Clinical, Regulatory, and Commercial organizations to ensure alignment on development priorities and execution.
- Represent Pharmaceutical Sciences in governance committees and executive reviews.
- Influence senior leadership decisions through data-driven scientific and operational recommendations.
- Collaborate with Regulatory Sciences and Regulatory Affairs on CMC strategy, risk mitigation, and agency responses.
- Represent Pharmaceutical Sciences in interactions with global health authorities and regulatory inspections, as needed.
- Participate in due diligence activities, external scientific collaborations, and business development evaluations.
- Build strong relationships with external partners, vendors, and industry organizations.
- Implement scalable systems, processes, and metrics to improve development efficiency and execution quality.
- Foster an inclusive and performance-oriented culture that embodies company leadership values and behaviors.
Requirements
- PhD or equivalent advanced degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biochemistry, or related scientific discipline preferred.
- 15+ years of progressive pharmaceutical or biotechnology industry experience, including significant leadership responsibility in Pharmaceutical Sciences, CMC, or Technical Operations.
- Experience leading multidisciplinary scientific teams in matrixed global organizations.
- Strong knowledge of pharmaceutical development, manufacturing, analytical development, regulatory expectations, and quality systems.
- Experience managing external manufacturing and development partners (CMOs/CDMOs/CROs).
- Strategic thinker with strong scientific and operational acumen.
- Exceptional communication and influencing skills with executive presence.
- Proven ability to drive alignment across complex cross-functional organizations.
- Strong decision-making and problem-solving capabilities in dynamic development environments.
- Prior experience in NDA/MAA submissions and regulatory approvals.
- Experience supporting commercial manufacturing and lifecycle management activities.
- Familiarity with global supply chain strategy and technical operations.
- Experience in both large pharmaceutical and emerging biotech environments preferred.
Skills
- Pharmaceutical development
- CMC strategy
- Formulation development
- Analytical development
- Process development
- Manufacturing
- Technology transfer
- Regulatory submissions
- Lifecycle management
- Regulatory knowledge
- Quality knowledge
- Scientific leadership
- Team leadership
- Cross-functional leadership
- Communication skills
- Influencing skills
- Decision-making
- Problem-solving
- Due diligence
- External collaborations
- Business development
- Supply chain strategy
- Technical operations
Location
- San Francisco
Work Type
- Hybrid
- On-site
- Travel
Experience Level
- 15+ years of progressive pharmaceutical or biotechnology industry experience
- Significant leadership responsibility
Education Level
- PhD or equivalent advanced degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biochemistry, or related scientific discipline
Salary/Compensations
- $267,000—$331,900 USD
Benefits
- Market-leading compensation
- 401(k) with employer match
- Employee Stock Purchase Program (ESPP)
- Pre-tax commuter benefits (transit and parking)
- Referral bonus for hired candidates
- Subsidized lunch and parking on in-office days
- 100% employer-paid medical, dental, and vision premiums for you and your dependents
- Health Savings Account (HSA) with annual employer contributions
- Flexible Spending Accounts (FSA)
- Fertility & family-forming benefits
- Expanded mental health support (therapy and coaching resources)
- Flexible, “take-what-you-need” paid time off and company-paid holidays
- Comprehensive paid medical and parental leave
- Career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching
About the Company
- In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation.
- This model allows science and small teams of experts to lead the way.
- We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.
- Together we define white space, push boundaries, and empower people to solve problems.
- If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry.
- Together, we'll ask "why not?" and help reengineer the future of biopharma.
- At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.