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Responsibilities
- Plan, design, conduct, establish, analyze, and validate bioanalytical experiments based on ligand binding assays (LBA), including pharmacokinetic (PK), anti-drug antibody (ADA), total antibody (TAb), and neutralizing antibody (NAb) studies, following given method development instructions.
- Perform biological sample analysis using established and qualified ligand binding methods.
- Independently familiarize yourself with relevant documents and ensure compliance with all applicable requirements and guidelines.
- Analyze and evaluate results using Precision Laboratory Information Management System (LIMS), Microsoft Excel, and GraphPad Prism.
- Support processes related to the Laboratory Information Management System (LIMS).
- Compile and prepare results for overviews, development progress, presentations, and other documentation formats.
- Review study- and department-related documents, e.g., SOPs, validation protocols, validation reports, notes-to-file, LIMS experiment protocols, protocol templates, and forms.
- Maintain laboratory equipment and take responsibility for assigned equipment.
- Be responsible for the autoclaving of liquid and solid laboratory waste.
- Manage reagents at various storage temperatures, maintain material and reagent inventory for all projects, and support ordering processes.
- Maintain and update clinical sample data in the respective systems.
- Contribute to the creation, optimization, and adherence to procedures and required SOP documentation for PK and ADA methods, as well as other department-related documents.
- Ensure compliance with laboratory, environmental, health, and safety (EHS) regulations and actively support corresponding safety measures.
Requirements
- Completed degree in Biology, Biochemistry, Biotechnology, Pharmacy, Chemistry, or a comparable natural science field.
- First experience in bioanalysis or ligand binding assays (LBA) is advantageous.
- Knowledge of PK, ADA, TAb, and/or NAb analyses is desirable.
- Experience with LIMS systems, Microsoft Excel, and GraphPad Prism.
- Careful, structured, and quality-oriented way of working.
- Good team and communication skills.
- Very good German and good English skills, both written and spoken.
Skills
- Ligand Binding Assays (LBA)
- Pharmacokinetics (PK)
- Anti-Drug Antibody (ADA)
- Total Antibody (TAb)
- Neutralizing Antibody (NAb)
- Laboratory Information Management System (LIMS)
- Microsoft Excel
- GraphPad Prism
- Method Development
- Bioanalysis
- EHS Regulations
Experience Level
- First experience in bioanalysis or ligand binding assays (LBA) is advantageous.
Education Level
- Completed degree in Biology, Biochemistry, Biotechnology, Pharmacy, Chemistry, or a comparable natural science field.
About the Company
- Precision Medicine Group is an Equal Opportunity Employer.
Equal Opportunity
- Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.
- If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at myHR@precisionmedicinegrp.com.