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About the Role
ORIC Pharmaceuticals is seeking an experienced Senior Scientist to provide lab support across various projects and teams, contributing to the mission of bringing new therapies to cancer patients.
Responsibilities
- Independently lead analytical development and product characterization activities for one or more molecules in CMC development.
- Develop and optimize analytical methods to support early and late-stage development.
- Solve challenging problems using traditional or emerging analytical techniques.
- Design experiments and perform sample analysis using general laboratory techniques.
- Operate laboratory instruments such as HPLC, LC-MS, GC, UV-Vis, KF, DSC, TGA, XRPD.
- Execute analysis with a solid understanding of test procedures, underlying science, and proper instrument operation.
- Utilize software to control instruments, collect data, process results, and prepare reports.
- Maintain precise and comprehensive records of all analyses in a lab notebook in real time.
- Prepare presentation materials and communicate research results to management.
- Present research findings at internal meetings.
- Author/review technical reports, technical packages, and relevant sections in health authority filings.
Requirements
- M.Sc. degree in chemistry with >8 years of relevant research experience, or a Ph.D. degree with a minimum of 3 years of hands-on pharmaceutical/biotech industry experience, or equivalent.
- Hands-on experience with laboratory techniques, including chromatography (e.g., HPLC, GC, LC/MS), spectroscopy (e.g., UV-Vis, FTIR), titration methods (e.g., Karl Fischer, acid-base), dissolution testing, particle size analysis (by laser diffraction), microscopy, and other compendial methods.
- Experience using laboratory software to collect, analyze, and report data.
- Strong attention to detail.
- Demonstrated prior experience working in GLP, cGMP environment.
- Demonstrated ability to take initiative, ownership, problem identification, problem solving and strategic input.
- Excellent communication and organization skills.
- Ability to work independently and efficiently collaborate in a fast-paced, integrated, multidisciplinary team environment.
- Exceptional problem-solving skills, scientific curiosity, critical thinking, and ability to quickly adapt and shift focus as needed.
- Experience working in late-stage development or commercialization environments is preferred.
- Hands-on in-plant experience within a manufacturing or production setting is highly preferred.
Skills
- Analytical development
- Product characterization
- Chromatography (HPLC, GC, LC/MS)
- Spectroscopy (UV-Vis, FTIR)
- Titration methods (Karl Fischer, acid-base)
- Dissolution testing
- Particle size analysis (laser diffraction)
- Microscopy
- Compendial methods
- Laboratory software (Openlab, Empower, Excel)
- GLP
- cGMP
- Problem identification
- Problem solving
- Strategic input
- Communication skills
- Organization skills
- Collaboration
- Critical thinking
- Adaptability
Location
- South San Francisco, California
Work Type
- On-site
Experience Level
- Senior Scientist
-
8 years of relevant research experience (M.Sc.)
- 3 years of hands-on pharmaceutical/biotech industry experience (Ph.D.)
Education Level
- M.Sc. in chemistry
- Ph.D.
Salary/Compensations
- $75.00-$85.00/ per hour
About the Company
- ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer.
- ORIC’s clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers.
- ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms.
- ORIC has offices in South San Francisco and San Diego, California.
Equal Opportunity
- ORIC Pharmaceuticals, Inc. is an equal opportunity employer.
- ORIC does not discriminate based on race, color, religion, gender, sexual orientation, gender identity, age, national origin, disability status, protected veteran status, or any other legally protected characteristics.