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About the Role
The Chief of Staff will partner directly with the Head of Life Sciences and Curing Diseases to translate strategy into execution, ensure program effectiveness during scaling, and act as a force multiplier. This role involves owning critical workstreams, driving clarity in ambiguous situations, and building systems to deploy capital for scientific and health impact.
Responsibilities
- Drive execution across the Life Sciences and Curing Diseases portfolio.
- Translate high-level strategy into concrete priorities, roadmaps, and operating plans.
- Track progress across multiple focus areas, ensuring work advances with urgency and clarity.
- Identify bottlenecks and intervene directly to unblock critical initiatives.
- Act as a force multiplier for the Head of Life Sciences and Curing Diseases.
- Partner closely on decision-making, prioritization, and external engagements.
- Prepare materials, synthesize inputs, and ensure high-quality outputs across key initiatives.
- Step in to represent the program lead in internal and external settings when needed.
- Build and run the operating system for the program.
- Establish processes for planning, resource allocation, and execution across a rapidly growing portfolio.
- Create visibility across workstreams, ensuring leadership has a clear view of what is happening and what matters.
- Implement lightweight but effective systems that scale with the program.
- Own critical cross-functional initiatives.
- Lead special projects that cut across focus areas, including launching new initiatives, standing up new grantmaking efforts, and building partnerships.
- Coordinate with finance, legal, communications, operations, and external partners to move complex efforts forward.
- Help design and operationalize new focus areas before dedicated leads are in place.
- Support hiring and team buildout.
- Help identify talent gaps and drive recruiting for key roles across the life sciences portfolio.
- Act as a cultural anchor for a high-performance, mission-driven team.
- Onboard new team members and ensure they are set up to succeed quickly.
Requirements
- 5+ years of relevant experience required; 8–12+ years preferred.
- Relevant experience in areas such as program management, strategy and operations, Chief of Staff work, life sciences, biotechnology, global health, translational medicine, public health, philanthropy, or related fields.
- Demonstrated ability to manage complex cross-functional workstreams and drive execution in ambiguous environments.
- Strong organizational and operational judgment, with the ability to build processes that improve clarity, speed, and effectiveness.
- Excellent written and verbal communication skills, including the ability to synthesize complex information clearly and persuasively.
- Experience working with senior leaders and supporting high-stakes decision-making.
- Ability to engage credibly with scientific, technical, operational, and external stakeholders.
- High degree of ownership, discretion, and accountability.
- Strong strategic judgment combined with a bias toward execution.
- Deep motivation to help accelerate progress in life sciences and contribute to the Foundation’s mission.
Skills
- Program management
- Strategy and operations
- Strategy consulting
- Program leadership
- Early-stage startups
- Turning ambiguous problems into structured plans
- Context-switching across domains
- Scientific
- Operational
- Strategic
- Communication
- Working with technical teams
- Working with scientific teams
- Working with highly specialized teams
- Life sciences
- Biotechnology
- Global health
- Translational medicine
- Public health
- Philanthropy
Experience Level
- 5-12+ years of experience
Salary/Compensations
- $244,000 to $336,000 USD
About the Company
- AI is already changing how people work, learn, and access care, with the potential to unlock extraordinary benefits across various sectors.
- The Foundation aims to enable the use of AI to find solutions to humanity’s hardest problems, transform human capabilities, and deliver real benefits, while preparing for new challenges and enhancing societal resilience.
- The Foundation expects to invest at least $1 billion over the next year across life sciences, curing diseases, jobs and economic impact, AI resilience, and community programs.
- The Life Sciences and Curing Diseases program aims to accelerate progress on curing diseases and improving human health, with initial focus areas including AI for Alzheimer’s, Public Data for Health, and Accelerating Progress on High-Mortality and High-Burden Diseases.
Equal Opportunity
- We are an equal opportunity employer and do not discriminate on the basis of race, religion, national origin, gender, sexual orientation, age, veteran status, disability or any other legally protected status.
- Pursuant to the San Francisco Fair Chance Ordinance, we will consider qualified applicants with arrest and conviction records.