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About the Role
The OpenAI Foundation is establishing its life sciences program to accelerate progress in curing diseases and enhancing human health. This program will initially concentrate on AI for Alzheimer's, Public Data for Health, and High-Burden Diseases. We are seeking a Program Officer, High-Burden Diseases to help build this initiative from its inception. This role involves investing in AI and data applications to advance R&D for preventing and treating high-burden diseases globally. As a founding member of the Life Sciences and Curing Diseases program, this generalist position requires flexibility to work across various focus areas, source and evaluate opportunities, engage with external organizations, support strategy development, and deploy significant resources.
Responsibilities
- Help source, evaluate, and recommend grants and other funding opportunities across multiple domains within the High-Burden Diseases program
- Support research of new disease or technology areas and determine where the Foundation should focus and develop investment theses
- Conduct diligence on organizations, projects, and leaders, assessing scientific value, execution capability, data quality, and potential for real-world impact
- Help design and manage a growing portfolio of grants, ensuring strong judgment, clear prioritization, and high-quality follow-through
- Work closely with the Head of High-Burden Diseases to shape strategy, prioritize opportunities, and refine the Foundation’s approach
- Engage deeply with the external ecosystem, including researchers, nonprofits, academic centers, public-interest organizations, data platforms, funders, and other potential grantee organizations
- Build and maintain strong relationships with leaders across biology, medicine, public health, data infrastructure, open science, and AI-enabled research
- Identify gaps in the current ecosystem and develop ideas for how the Foundation can support new efforts, partnerships, or field-building initiatives
- Support the creation of new initiatives from zero-to-one, including helping shape concepts, convene stakeholders, and stand up new efforts
- Write clear internal recommendations and strategy memos to support decision-making
- Represent the Foundation in external conversations, helping to build credibility, source opportunities, and strengthen the broader field
Requirements
- 7-10+ years experience strongly preferred, although earlier-career candidates with a track record of truly exceptional ability and accomplishment will be considered
- Relevant experience in areas such as biology, chemistry, translational medicine, drug development, clinical practice, global health, biotechnology, venture or grant investing in life sciences, or related fields
- Ability to engage credibly across a range of scientific and strategic topics
- Demonstrated ability to evaluate scientific, technical, or organizational opportunities and make strong recommendations
- Experience engaging credibly with external experts, institutions, and other stakeholders
- Excellent written and verbal communication skills, including the ability to synthesize complex information clearly and persuasively
- Strong judgment, follow-through, and comfort operating with meaningful autonomy
- Ability to work effectively in a highly ambiguous, evolving environment
- High degree of ownership, discretion, and accountability
- Deep motivation to help accelerate progress in life sciences and contribute to the Foundation’s mission
Skills
- AI for Alzheimer's
- Public Data for Health
- High-Burden Diseases
- AI and data applications
- Scientific evaluation
- Strategic thinking
- Grantmaking
- Relationship building
- Communication
- Judgment
- Adaptability
Location
- San Francisco, CA (strongly preferred)
Work Type
- Hybrid (3 days in office per week)
- Some travel required
Experience Level
- 7-10+ years
Salary/Compensations
- $220,000 to $330,000 USD
About the Company
- AI is transforming how people work, learn, and access care, with the potential for significant benefits in areas like medical breakthroughs, scientific discovery, personalized services, creativity, productivity, economic growth, and public services.
- The Foundation aims to enable AI to solve humanity's hardest problems, enhance human capabilities, and deliver tangible benefits, while proactively addressing emerging challenges and building societal resilience.
- The Foundation plans to invest at least $1 billion over the next year in life sciences, curing diseases, jobs and economic impact, AI resilience, and community programs, including contributions to its $25 billion commitment for curing diseases and AI resilience.
Equal Opportunity
- We are an equal opportunity employer and do not discriminate on the basis of race, religion, national origin, gender, sexual orientation, age, veteran status, disability or any other legally protected status.
- Pursuant to the San Francisco Fair Chance Ordinance, we will consider qualified applicants with arrest and conviction records.