Head of AI for Alzheimer’s at OpenAI Foundation | CA, US | Rezi

Head of AI for Alzheimer’s at OpenAI Foundation

Head of AI for Alzheimer’s

OpenAI Foundation · CA, US

Today

Head of AI for Alzheimer’s

OpenAI Foundation · CA, US

10 hours ago
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About the Role

The OpenAI Foundation is establishing a Life Sciences and Curing Diseases program, with an initial focus on AI for Alzheimer's. This founding role will shape strategy, identify opportunities, and deploy resources to accelerate progress against Alzheimer's disease. The ideal candidate is flexible, thoughtful, action-oriented, comfortable with ambiguity, and skilled at engaging external experts to translate a broad mission into a focused portfolio.

Responsibilities

  • Develop clear theses for how the Foundation can accelerate progress towards preventing and treating Alzheimer's.
  • Deploy hundreds of millions of dollars towards the goal of preventing and treating Alzheimer's.
  • Work closely with the Head of Life Sciences and Curing Diseases to shape strategy, prioritize opportunities, and refine the Foundation’s approach.
  • Source, evaluate, and recommend grants and other funding opportunities.
  • Conduct diligence on organizations, projects, and leaders, assessing scientific value and potential for real-world impact.
  • Engage deeply with the external ecosystem, including researchers, nonprofits, public health organizations, startups, academic centers, funders, and other potential grantee organizations.
  • Build and maintain strong relationships with leaders across Alzheimer’s research and AI for science.
  • Prepare clear internal briefs, recommendations, and memos to support decision-making.

Requirements

  • 10-15+ years of relevant experience preferred.
  • Relevant experience in areas such as Alzheimer’s research, neuroscience, neurology, biotechnology, translational medicine, venture or grant investing in life sciences, or related fields.
  • Strong interest in the role AI can play in accelerating Alzheimer’s research, including in areas such as data analysis, biomarker discovery, disease modeling, clinical development, or therapeutic discovery.
  • Demonstrated ability to evaluate scientific, technical, or organizational opportunities and make strong recommendations.
  • Experience engaging credibly with external experts, institutions, and senior stakeholders.
  • Excellent written and verbal communication skills, including the ability to synthesize complex information clearly and persuasively.
  • Strong strategic judgment combined with a bias toward execution.
  • Ability to work effectively in a highly ambiguous, evolving environment.
  • High degree of ownership, discretion, and accountability.
  • Deep motivation to help accelerate progress in life sciences and contribute to the Foundation’s mission.

Skills

  • AI for Alzheimer's
  • Data analysis
  • Biomarker discovery
  • Disease modeling
  • Clinical development
  • Therapeutic discovery
  • Scientific evaluation
  • Technical evaluation
  • Organizational evaluation
  • External engagement
  • Strategic judgment
  • Execution bias
  • Ambiguity tolerance
  • Ownership
  • Discretion
  • Accountability

Location

  • San Francisco Bay Area

Work Type

  • Full-time

Experience Level

  • 10-15+ years

Salary/Compensations

  • $430,000 to $580,000 USD

About the Company

  • AI is transforming work, learning, and healthcare, with the potential for significant benefits like faster medical breakthroughs, accelerated scientific discovery, and improved productivity. The OpenAI Foundation aims to enable AI to solve humanity's hardest problems and deliver real benefits, while also preparing for new challenges and enhancing societal resilience as AI advances. The Foundation plans to invest at least $1 billion over the next year in life sciences, curing diseases, jobs and economic impact, AI resilience, and community programs, including prior commitments to curing diseases and AI resilience.

Equal Opportunity

  • We are an equal opportunity employer and do not discriminate on the basis of race, religion, national origin, gender, sexual orientation, age, veteran status, disability or any other legally protected status.
  • Pursuant to the San Francisco Fair Chance Ordinance, we will consider qualified applicants with arrest and conviction records.