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About the Role

This position in the Quality Control (QC) Team is responsible for initial sample handling, including nucleic acid extractions, initial sample QC, and genotyping on the Illumina Infinium platform.

Responsibilities

Carry out procedures associated with DNA & RNA for sequencing platforms, including DNA/RNA sample extraction, quantification & preparation, Illumina Infinium genotyping
Assist with library preparation and sequencer operation for Illumina NovaSeq X, Ultima UG100, Oxford Nanopore PromethION, PacBio Revio platforms, as needed
Perform quality control of initial samples and sequencing ready final library samples
Perform sample nucleic acid extraction with the use of automation (Hamilton Star, KingFisher Flex, QIAcube Connect)
Process DNA for Illumina microarray platforms with use of automation (Hamilton Star, Tecan, iScan)
Conduct other laboratory work, as needed
Track all work and issues in the appropriate databases and Laboratory Information Management Systems (LIMS)
Become proficient using NYGC’s LIMS tracking system to accurately perform day-to-day tasks
Perform monthly instrument maintenance on laboratory equipment, in accordance to instrument SOPs

Requirements

Bachelors’ degree in Molecular Biology, Biotechnology, Biochemistry or related field, plus laboratory experience in nucleic acid research required
1 year of experience in a molecular biology lab
Experience with automated liquid handlers preferred
Experience in next-generation sequencing a plus
Solid knowledge of molecular biology equipment and related protocols (including RNA and DNA preparation, RNA and DNA quantification, hybridization, PCR, multiplex amplification and bead-based solutions) highly preferred
Familiarity with Microsoft Word, Excel, and PowerPoint, preferably with Mac OS
Good general laboratory and organizational skills, including the ability to work independently and efficiently are essential
Ability to multitask is a must, along with an orientation toward teamwork and cooperation
Strong creative thinking and problem-solving skills
Excellent communication skills required

Skills

DNA & RNA extraction
Sample quantification & preparation
Illumina Infinium genotyping
Library preparation
Sequencer operation
Quality control
Automated liquid handlers
Next-generation sequencing
RNA and DNA preparation
RNA and DNA quantification
Hybridization
PCR
Multiplex amplification
Bead-based solutions
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
Mac OS
Laboratory Information Management Systems (LIMS)

Location

Lower Manhattan

Work Type

Full-time
Exempt

Experience Level

Associate Scientist I
1 year of experience

Education Level

Bachelors’ degree

Salary/Compensations

$57,000-67,000 per year

Benefits

Medical/Dental/Vision for employees & dependent(s)
Vacation, Holidays, Sick, and Other Leave, including a paid winter break
401(k) match
Life Insurance
Flexible Spending Accounts
Employee Tuition Reimbursement
Flexible schedules
Telework options for some positions
Employee Assistance Program

About the Company

The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research.
NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools.
NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.
Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions.
Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university.
They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.

Equal Opportunity

We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive.
We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery.
Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success.
We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization.
The New York Genome Center is a VEVRAA Federal Contractor.
All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law.
NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities.