Senior Principal Scientist - Microscopy at Regeneron Pharmaceuticals | NY, US | Rezi

Senior Principal Scientist - Microscopy at Regeneron Pharmaceuticals

Senior Principal Scientist - Microscopy

Regeneron Pharmaceuticals · NY, US

Yesterday

Senior Principal Scientist - Microscopy

Regeneron Pharmaceuticals · NY, US

2 days ago
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About the Role

Regeneron is seeking an accomplished and innovative scientist to lead the Microscopy function within Imaging Sciences. This individual will provide scientific and strategic leadership for a multidisciplinary microscopy team supporting discovery research, technology development, translational science, and early therapeutic programs. The role will drive the future vision of imaging sciences through the adoption of emerging microscopy technologies, automation, AI-enabled analytics, and integrated imaging solutions.

Responsibilities

  • Advance the scientific direction for microscopy and cellular imaging across Regeneron Research.
  • Identify, evaluate, validate, and adopt emerging technologies based on scientific value, technical performance, scalability, and portfolio need.
  • Provide senior consultation that translates complex biological questions into fit-for-purpose imaging strategies, experimental designs, and quantitative readouts.
  • Lead, develop, and retain a high-performing multidisciplinary microscopy team and foster a culture of scientific rigor, collaboration, innovation, and continuous learning.
  • Oversee annual strategic, operational, workforce, and capital-equipment plans for the microscopy function.
  • Establish governance, metrics, workflows, training, and service models that improve quality, accessibility, reliability, turnaround time, and scientific impact.
  • Provide scientific leadership across advanced optical, super-resolution, spectral, lifetime, label-free, live-cell, 3D, high-content, high-throughput, spatial, and translational microscopy approaches.
  • Guide method selection, assay development, experimental design, technology troubleshooting, and quantitative image analysis, including machine-learning-enabled approaches.
  • Develop scalable imaging infrastructure spanning laboratory automation, robotic image acquisition, image-data management, cloud analytics, AI applications, and digital microscopy.
  • Integrate microscopy with molecular imaging, histology, pathology, spatial biology, and other Imaging Sciences platforms.
  • Partner with discovery, translational, platform, engineering, data science, and technology teams to deliver imaging strategies.
  • Mentor microscopy scientists and imaging specialists, build technical depth and scientific leadership, and train researchers in microscopy best practices and experimental design.

Requirements

  • A Ph.D. in Cell Biology, Cellular Physiology, Developmental Biology, Molecular Biology, Bioengineering, Biophysics, or related discipline.
  • Minimum 5 years of relevant postdoctoral and/or industry experience.
  • Minimum 5 years leading a microscopy core facility or equivalent scientific organization.
  • Demonstrated expertise developing and applying advanced microscopy methodologies to answer complex biological questions.
  • A strong publication record with evidence of leadership as a primary or senior contributor in microscopy-driven research.
  • Deep understanding of cell biology, optical physics, microscopy instrumentation and mechanics, image formation, fluorescent probes and reporters, automation, and quantitative image analysis.
  • Experience selecting, implementing, and optimizing advanced microscopy imaging platforms.
  • Demonstrated success managing scientific staff and multidisciplinary teams.
  • Strong project management and stakeholder engagement experience.
  • Recognized external reputation in biological microscopy or imaging sciences.
  • Experience building or transforming an imaging core facility.
  • Working knowledge of machine learning and AI-driven image analysis.
  • Experience with spatial omics and multiplexed imaging platforms is desirable but not required.
  • Experience integrating microscopy with in vivo imaging, pathology, and translational biomarker efforts.
  • Record of successful strategic technology adoption and innovation.

Skills

  • Microscopy
  • Cell biology
  • Advanced optical imaging technologies
  • Quantitative image analysis
  • Scientific leadership
  • Advanced optical microscopy
  • Super-resolution microscopy
  • Spectral microscopy
  • Lifetime microscopy
  • Label-free microscopy
  • Live-cell microscopy
  • 3D microscopy
  • High-content microscopy
  • High-throughput microscopy
  • Spatial microscopy
  • Translational microscopy
  • Machine-learning-enabled approaches
  • Automation
  • AI-enabled analytics
  • Multidimensional imaging workflows
  • Integrated imaging solutions
  • Molecular imaging
  • Histology
  • Pathology
  • Spatial biology
  • Project management
  • Stakeholder engagement

Location

  • Tarrytown, NY United States

Work Type

  • On-site

Experience Level

  • Senior Principal
  • Minimum 5 years of relevant postdoctoral and/or industry experience
  • Minimum 5 years leading a microscopy core facility or equivalent scientific organization

Education Level

  • Ph.D. in Cell Biology, Cellular Physiology, Developmental Biology, Molecular Biology, Bioengineering, Biophysics, or related discipline

Salary/Compensations

  • $150,500.00 - $245,500.00

Benefits

  • Annual bonuses or other incentive plans
  • Equity awards
  • Pension or retirement benefits
  • 401(k) company match
  • Health and wellness programs
  • Fitness centers
  • Insurance benefits (e.g. medical, dental, vision, life and disability)
  • Paid time off
  • Family support benefits

About the Company

  • Regeneron is committed to building a workplace with an inclusive culture.
  • We believe we do our best work when we are together.
  • As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based.
  • The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

Equal Opportunity

  • Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.
  • Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.