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About the Role

AstraZeneca is seeking a highly qualified Global Clinical Program Lead (GCPL) to spearhead the clinical development and execution of product strategies for multiple Hematology projects. This role is crucial for advancing science and delivering life-changing medicines to patients in need, reporting to the Global Clinical Head of the disease indication.

Responsibilities

Leads clinical development teams for novel Hematology Oncology therapies from preclinical candidate selection through proof of concept leading to Phase 3 investment decisions.
Leads all regulatory submissions.
Accountable for the clinical strategy and clinical execution of a portfolio of pre-clinical and clinical stage therapies.
Accountable for the delivery of projects according to quality, time, budgets, and resources.
Builds strategic and coordinated clinical development plans aligned with business objectives and differentiated from competitor products.
Accountable for the execution of the integrated product plan to agreed scope, timelines, and budgets.
Leads and communicates the clinical development strategy at governance meetings, aligning with internal management and communicating with external collaborators.
Leads clinical aspects of projects from preclinical Lead Optimization Investment Decision to clinical Proof of Concept (PoC).
Responsible for all clinical aspects of project strategy including translational, clinical development, patient selection, regulatory, pediatric, and Asian development strategy.
Development of the Target Product Profile, ensuring alignment with disease area strategy and late stage development.
Co-leads the Clinical Program Team (CPT) to effectively run/mitigate/communicate risk, make decisions, and handle conflict and change.
Responsible for maintaining a high degree of CPT effectiveness through collaboration, influence, and coaching/mentoring of cross-functional team members.
Ensures robust processes, plans, and data to enable Governance Bodies to make investment decisions and prioritize projects across the portfolio.

Requirements

M.D. is required.
A minimum of 7 years of relevant experience.
Industry experience in drug development including experience in early and late phase drug development and regulatory knowledge.
Strong knowledge and understanding of the Hematology Oncology therapeutic area with experience in diverse biological mechanisms.
Broad understanding of the evolving clinical landscape in hematology/oncology.
Lead the overall development of project strategy and be accountable for project plans, timelines, progress, and outcomes.
Proven experience mentoring and motivating teams in a highly matrixed environment.
Proven record of encouraging and leading internal and external cross-functional collaborations.
Demonstrated organizational and project management skills.
Proven success in influencing colleagues and senior leaders in various departments.
Must demonstrate high integrity.

Skills

Hematology/oncology clinical drug development
Leadership
Critical navigation of science
Effective communication across broad audiences
Articulating project specific strategies
Articulating overall oncology strategy
Collaboration
Influence
Coaching
Mentoring

Location

Hybrid

Work Type

Hybrid
Full-time

Experience Level

Minimum of 7 years of relevant experience

Education Level

M.D.

Salary/Compensations

$288,059 - $432,088

Benefits

Short-term incentive bonus opportunity
Equity-based long-term incentive program (salaried roles)
Retirement contribution (hourly roles)
Commission payment eligibility (sales roles)
Qualified retirement program [401(k) plan]
Paid vacation and holidays
Paid leaves
Health benefits including medical, prescription drug, dental, and vision coverage

About the Company

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company focused on the discovery, development, and commercialization of prescription medicines for serious diseases.
AstraZeneca has a multifaceted environment that cultivates collaboration and innovation.
We attract top minds, and we nurture and build talent.
Within Hematology R&D, we are committed to advancing the science to deliver life-changing medicines to patients most in need.
Our combination-focused pipeline exploits six scientific platforms to address unmet clinical needs in hematological cancers.
We are motivated by a dedication to scientific discovery and collaboration to help eliminate cancer as a cause of death.
This unit has responsibility for the value chain from discovery through to late-stage development.
The Hematology Research and Early Development (R&D) team has accountability for all drug development activities in hematology research from first in man studies to late-stage trials leading to drug approval.
The team strives to deliver compelling preclinical, clinical and translational data packages to support investment in late stage clinical development.
At AstraZeneca, you'll have the chance to create a substantial difference to patients’ lives.
With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines for the world’s most complex diseases.
Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and crafting the patient ecosystem.

Equal Opportunity

AstraZeneca embraces diversity and equality of opportunity.
We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.
We believe that the more inclusive we are, the better our work will be.
We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.
We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees.
In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics.
If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.