Executive Director Clinical Operations, Program Management (Cell Therapy)
AstraZeneca · CA, US
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About the Role
Lead global cell therapy clinical operations across multiple franchises, translating strategy into execution for early development cell therapies. Partner with senior leaders to shape franchise strategies, drive standardization, and ensure inspection-ready excellence for a global team.
Responsibilities
- Define and implement short- and long-term clinical operations strategies across franchises.
- Provide direct strategic oversight of global cell therapy clinical studies to meet time, cost, quality, and regulatory standards.
- Serve as a core member of enterprise governance for cell therapy, including Protocol Review Committee sign-off.
- Establish and communicate delivery strategies, portfolio priorities, and key metrics to leadership.
- Ensure franchise-wide preparation for regulatory submissions and sustained inspection readiness.
- Build and inspire a strong, capable global team across program leadership roles.
- Lead functional delivery including financial cycle planning, training and onboarding strategies, and functional budget management.
- Build deep partnerships with shared functions to co-create and execute cell therapy strategies.
- Engage with industry leaders to bring innovation into clinical operations practice.
- Serve as a key member of the leadership team, shaping the forward plan and ensuring standardization of delivery across programs.
Requirements
- Bachelor’s degree or equivalent
- 12+ years of proven Drug Development experience, with direct experience in clinical drug development setting, including direct clinical operations experience
- Line management expertise; experience of performance management of Snr Director level Staff in a large pharmaceutical or biotech setting of teams of 20+
- Demonstrated development of others, identifying and providing opportunities to improve the capabilities of other people
- Functional Experience in contributing meaningfully to Clinical Operations functional improvement initiatives that cross clinical programs management experience, managing resourcing, budget planning and functional level activities
- Background of high professional achievement and willingness to encourage this in others
- Leads change with a positive approach; sees change as an opportunity to improve performance and add value to the business
- Influencing and stakeholder management
- Supplier/Partnership Management
- Excellent communication skills - Demonstrated ability to set and manage priorities, resources, performance targets and project initiatives in a global environment
- Creative and Innovative: Seeks to improve continuously where it counts, based on good awareness of external competitive practice, and creativity and initiative
- Output/delivery focused - Maintains high standards, including a commitment to AstraZeneca values, policies and employment principles
- Cultural Awareness: Is aware of and sensitive to cultural differences and their impact on communication, expectations and performance.
- Teamwork and cross functional Collaboration: Is effective in leading and being a member of teams, both locally and internationally.
- Willingness to travel domestically and internationally
Skills
- Drug Development
- Clinical Drug Development
- Clinical Operations
- Line Management
- Performance Management
- Functional Improvement Initiatives
- Resourcing
- Budget Planning
- Professional Excellence
- Change Leadership
- Influencing
- Stakeholder Management
- Supplier Management
- Partnership Management
- Communication
- Priority Setting
- Resource Management
- Performance Target Setting
- Project Initiative Management
- Creativity
- Innovation
- Cultural Awareness
- Teamwork
- Cross-functional Collaboration
Location
- Gaithersburg, MD
- Boston, MA
- SSF, CA
- Santa Clara, CA
- US based
Work Type
- Full-time
- Hybrid
Experience Level
- 12+ years
- 15+ years
Education Level
- Bachelor’s degree or equivalent
- Advanced Degree (M.S, MBA, PhD)
Salary/Compensations
- $270,188.80 - 405,283.20 USD
Benefits
- Short-term incentive bonus opportunity
- Equity-based long-term incentive program
- Retirement contribution
- Qualified retirement program (401(k) plan)
- Paid vacation and holidays
- Paid leaves
- Health benefits including medical, prescription drug, dental, and vision coverage
About the Company
- We harness cutting-edge science and modern platforms to change outcomes for patients, backed by sustained investment and a proven record of bringing multiple new cancer medicines to market in the past decade.
- We bring clinicians, scientists, data experts, and manufacturing leaders together to solve the hardest problems in cell therapy, with the autonomy to ask bold questions and the support to deliver at scale.
- Your leadership will shape how bench breakthroughs become global studies and, ultimately, new standards of care.
- We value kindness alongside ambition, pairing high expectations with collaboration, transparency, and the freedom to innovate.
Equal Opportunity
- We build an inclusive environment where equal employment opportunities are available to all applicants and employees.
- We welcome and consider applications from all qualified candidates, regardless of their protected characteristics.
- If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.