Research Scholar
NCIRE - The Northern California Institute for Research and Education, Inc. · CA, US
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About the Role
A postdoctoral scholar is needed to investigate the mechanisms by which respiratory pathogens, particularly fungal pathogens, cause disease in the human airway. This role involves developing and implementing laboratory assays, culturing fungal pathogens, and preparing for a career in human immunology.
Responsibilities
- Assist in maintaining and monitoring all equipment and procedures for quality control
- Review pertinent medical literature
- Design and execute experiments using cellular, biochemical, and molecular biology techniques
- Process human biological samples, including isolation of cells from blood and tissues; store and ship samples as needed
- Perform molecular biology procedures, including DNA and RNA isolation, reverse transcription, PCR, qPCR and qRT-PCR, ELISA, FISH, single-cell capture, sequencing library prep, and possibly others
- Perform cell culture procedures, including culture of cell lines and primary cells, transfection, in vitro infection, fluorescent microscopy, flow cytometry, single cell analysis methods, and possibly other techniques
- Implement, troubleshoot, optimize, and develop new assays, making innovative contributions to laboratory procedures
- Assist with the training of research methods and approaches to the laboratory group
- Maintain a detailed written record of work performed
- Perform analysis of experiment results and findings, including data collection, entry, statistical analysis (including computational analysis of sequencing data using R and/or Python), and graph creation
- Produce written reports detailing results of experiments and analysis of results, and draft manuscripts of results for publication
- Present oral and/or poster reports at laboratory, local, and national meetings
- Assist with the composition of grant applications
- Adhere to data security requirements
- Perform other duties as assigned
Requirements
- PhD in microbiology, immunology, or related science, MD, MD/PhD, or equivalent combination of education and experience
- 2+ years of related work experience desirable
- Knowledge of principles and practice of cellular and molecular biology
- Working knowledge of safety standards in laboratories
- Solid interpersonal skills
- Excellent organizational skills
- Careful attention to detail; ability to accurately follow experimental protocols
- Ability to manage multiple projects, tasks, and priorities to achieve desired goals
- Ability to meet deadlines
- Ability to think creatively and solve problems
- Ability to work under minimal supervision
- Strong written/oral communication skills
- Computer literacy with full working knowledge of MS Word/ or Overleaf/LaTeX or markdown, Excel, PowerPoint/Keynote, R, and graphing software
- Ability to analyze data and perform statistical analyses
- Ability to make sound decisions consistent with the essential job functions
- Must complete SFVA onboarding, including federal background check, occupational health clearance, vaccines and immunizations, and drug testing
- Must pass required drug testing, including screening for marijuana
Skills
- Cellular biology techniques
- Biochemical techniques
- Molecular biology techniques
- DNA isolation
- RNA isolation
- Reverse transcription
- PCR
- qPCR
- qRT-PCR
- ELISA
- FISH
- Single-cell capture
- Sequencing library prep
- Cell culture
- Transfection
- In vitro infection
- Fluorescent microscopy
- Flow cytometry
- Single cell analysis methods
- Assay development
- Data analysis
- Statistical analysis
- Computational analysis of sequencing data
- R
- Python
- Graph creation
- MS Word
- Overleaf/LaTeX
- Markdown
- Excel
- PowerPoint/Keynote
- Graphing software
Location
- San Francisco
Work Type
- Onsite
Experience Level
- Postdoctoral Scholar
- 2+ years of related work experience desirable
Education Level
- PhD in microbiology, immunology, or related science
- MD
- MD/PhD
- Equivalent combination of education and experience
Salary/Compensations
- $70,304.00 - $79,639.96 per year
About the Company
- NCIRE is an affiliate organization of the San Francisco VA Health Care System (SFVAHCS).
- This position requires access to United States Government research under the Veterans Administration.
Equal Opportunity
- NCIRE is an Equal Opportunity Employer.
- Per Veterans Administration regulations surrounding access to US research, qualified US Citizens will be selected over other individuals eligible to work in the United States. If you are eligible to work in the United States, you may still be considered for this position but only if no qualified US citizens apply.