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About the Role
This role focuses on building proprietary AI, machine-learning, and statistical models to predict clinical-trial outcomes and generate differentiated investment insights within a biotech and pharmaceutical equity research team.
Responsibilities
- Build AI and statistical models to predict clinical-trial results, probability of success, regulatory outcomes, and commercial potential.
- Analyze trial design, endpoints, powering, patient populations, treatment effects, safety, and subgroup data.
- Use generative AI, LLMs, and natural-language processing to analyze scientific publications, regulatory documents, trial registries, company disclosures, and earnings transcripts.
- Create automated tools to track pipelines, clinical catalysts, competitive programs, and emerging risks.
- Convert model outputs and clinical data into clear investment conclusions.
- Work with research analysts on company forecasts, pipeline valuations, and published research.
- Validate models and control for bias, overfitting, data leakage, and AI hallucinations.
Requirements
- PhD, MD, or master’s degree preferred in biostatistics, statistics, data science, artificial intelligence, epidemiology, bioinformatics, computational biology, medicine, or a related field.
- Strong Python or R skills.
- Experience building machine-learning, predictive, or generative-AI models.
- Strong knowledge of clinical-trial design and statistical analysis.
- Ability to explain complex scientific and quantitative findings clearly.
- Interest in biotechnology, drug development, investing, and financial markets.
- Equity-research experience is helpful but not required.
Skills
- Python
- R
- AI
- Machine Learning
- Statistical Modeling
- Generative AI
- LLMs
- Natural Language Processing
Location
- Primary Location
Work Type
- Full Time
Experience Level
- The salary offered will take into consideration an individual’s experience level and qualifications.
Education Level
- PhD
- MD
- Master's Degree
Salary/Compensations
- $135,000 - $165,000
Benefits
- Annual discretionary incentive and retention bonus
- Medical, dental & vision coverage
- 401(k)
- Life, accident, and disability insurance
- Wellness programs
- Paid time off packages that include planned time off (e.g., vacation)
- Unplanned time off (e.g., sick leave)
- Paid holidays
- Paid parental leave (for full-time employees)
About the Company
- Jefferies is a leading global, full-service investment banking and capital markets firm that provides advisory, sales and trading, research, and wealth and asset management services.
- With more than 40 offices around the world, we offer insights and expertise to investors, companies, and governments.
Equal Opportunity
- Jefferies is committed to building a culture that provides opportunities for all employees regardless of our differences and supports a workforce that is reflective of the communities where we work and live.
- Jefferies is committed to creating and sustaining a workforce that welcomes individuals from all backgrounds to apply.
- Our employment decisions are made without regard to race, creed, color, national origin, ancestry, religion, pregnancy, age, medical condition, physical or mental disability, marital status, domestic partner status, sex, sexual orientation, gender, gender identity or expression, veteran or military status, genetic information, reproductive health decisions, or any other factor protected by applicable law.
- We are committed to hiring the most qualified applicants and complying with all federal, state, and local equal employment opportunity laws.
- As part of this commitment, Jefferies will extend reasonable accommodation to individuals with disabilities, as required by applicable law.