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About the Role
You will provide technical leadership for the physical systems behind Capable’s drug-development platform, spanning areas like automated peptide synthesis, fluid handling, laboratory instrumentation, or subcutaneous drug delivery. You will own system architecture, make critical cross-disciplinary decisions, remain hands-on through prototype and validation, and help establish hardware development processes.
Responsibilities
- Own system architecture and technical direction for laboratory-automation or drug-delivery hardware, from requirements through validated prototypes.
- Design and integrate fluidic, electromechanical, sensing, control, and user-interface subsystems, balancing performance, reliability, safety, and speed of iteration.
- Resolve difficult design and integration problems involving flow paths, pressure, sealing, materials compatibility, actuation, thermal control, sensing, dose accuracy, carryover, priming, draining, or fault recovery.
- Define test strategies, acceptance criteria, and failure-analysis methods that connect engineering performance to chemical or biological outcomes.
- Build and debug critical prototypes personally while guiding the work of collaborators, vendors, and future hardware teammates.
- Partner closely with chemists, biologists, and software collaborators to decide what to automate, instrument, or redesign next.
- Establish practical engineering standards, documentation, component choices, and development workflows for Capable’s growing hardware function.
Requirements
- A strong record of owning complex physical systems from ambiguous requirements through working, tested hardware.
- Deep expertise in at least one relevant area—mechanical design, electrical systems, fluidics, controls, automation, medical devices, wearables, implantables, or laboratory instrumentation—and the judgment to work across the others.
- Exceptional hands-on debugging and root-cause analysis across hardware, controls, process conditions, and experimental outputs.
- The ability to make sound architectural tradeoffs, identify the highest-risk assumptions, and design fast tests that resolve them.
- Clear technical communication and the ability to lead cross-functional work without becoming removed from the hardware.
- We do not expect one person to have prior experience in every subsystem or application listed above.
Skills
- Mechanical design
- Electrical systems
- Fluidics
- Controls
- Automation
- Medical devices
- Wearables
- Implantables
- Laboratory instrumentation
- System architecture
- Technical leadership
- Hardware development
- Debugging
- Root-cause analysis
- Technical communication
Location
- San Francisco
Work Type
- Onsite
- Full-time
Experience Level
- Early-stage environment experience
- Technical leadership experience
Salary/Compensations
- $500+ monthly wellness budget
- Generous equity options
Benefits
- Medical coverage
- Dental coverage
- Vision coverage
- HSA
- FSA
- 401K plans
- Healthy dinners provided daily
- Visa sponsorship
About the Company
- We are a vibrant and intensely mission-driven team comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber.
- We value speed and rigor, coupled with excitement, drive, and a strong work ethic.
- In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy.
- Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better.
- You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems.
- We believe excellent work should be met with meaningful reward, ownership, and trust.
- Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope.
Equal Opportunity
- Capable is an Equal Opportunity Employer; employment with Capable is governed on the basis of merit, competence and qualifications and will not be influenced in any manner by race, color, religion, gender, national origin/ethnicity, veteran status, disability status, age, sexual orientation, gender identity, marital status, mental or physical disability or any other legally protected status.