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About the Role

Seeking an ambitious postdoctoral scientist with strong research and communication skills to contribute to a high-visibility research program at the intersection of cellular senescence biology, fibrosis, and immune-based therapeutics. Your work will contribute to establishing a precision senolytic approach that selectively eliminates pathological senescent cells in the fibrotic lung while sparing healthy tissue.

Responsibilities

Establish and characterize models of cellular senescence relevant to fibrotic lung disease, spanning primary human cells, iPSC-derived cells, and in vivo fibrosis models.
Identify and validate cell-surface markers that distinguish pathological senescent cells from healthy tissue, prioritizing candidates with a favorable safety profile.
Develop and engineer immune effector–based strategies to selectively eliminate senescent cells in the fibrotic lung.
Evaluate senolytic efficacy and its impact on fibrosis across disease-relevant human tissue and in vivo models.
Collaborate with cross-functional teams and external academic partners, present findings at major scientific conferences, and publish as first author.

Requirements

PhD in Immunology, Cell Biology, Molecular Biology, Aging Biology, or a closely related field.
Demonstrated experience with cellular senescence and at least one of the following: fibrosis, aging biology, immunology, therapeutic modality engineering (e.g., cell therapy, antibody, or protein engineering), or relevant analytical approaches such as proteomics or single-cell analysis.
Strong publication record demonstrating scientific productivity and independence.
Qualified applicants must be authorized to work in the United States on a full-time basis.
Lilly will not provide support for or sponsor work authorization and visas for this role.
This position is not permanent and requires US citizenship or permanent resident status.
It is for a fixed duration of two years with potential to extend to three years and for a maximum of up to four years.

Skills

Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.
Excellent communicator (oral and written) with presentation experience, along with a strong publication record.
Interest in cellular senescence, fibrosis biology, and translational drug discovery.
Background in cellular senescence or aging biology, including relevant cellular and in vivo models.
Hands-on expertise in immunology and immune cell biology.
Experience with therapeutic modality development, such as cell therapy, antibody, or protein engineering.
Familiarity with proteomic, transcriptomic, and/or high-parameter single-cell and imaging approaches.
Experience with human iPSC culture and directed differentiation.
Familiarity with disease-relevant human tissue and/or in vivo fibrosis models.
Strong analytical skills and the ability to integrate multi-modal datasets.

Location

Indianapolis, Indiana

Work Type

Full-time

Experience Level

Postdoctoral

Education Level

Salary/Compensations

$58,000 - $123,200

Benefits

Company bonus (depending, in part, on company and individual performance).
Company-sponsored 401(k).
Pension.
Vacation benefits.
Medical, dental, vision and prescription drug benefits.
Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts).
Life insurance and death benefits.
Certain time off and leave of absence benefits.
Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

About the Company

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters.
Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.
This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Equal Opportunity

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.