Impress employers and recruiters.
Choose from hundreds of resume examples.

Target Resume Now

About the Role

Manage external contract manufacturing organizations (CMOs) that manufacture and test drug substance and starting materials. Partner with discovery teams, Quality Assurance, and Regulatory Affairs to advance candidates from preclinical work into manufacturing, ensuring compliance with cGMPs and federal regulations. This role offers direct ownership of drug substance manufacturing with cross-functional visibility at a clinical-stage company.

Responsibilities

Direct international CMOs developing new chemical processes.
Design experiments to improve process efficiency.
Troubleshoot manufacturing issues.
Analyze existing production methods and recommend improvements to support clinical timelines.
Partner with Quality Assurance and Regulatory Affairs to ensure manufacturing stays compliant and audit-ready.
Prepare technical reports and present results to internal teams and external partners.
Track industry trends and advancements in chemical technology.
Accommodate global time zones for meetings outside standard business hours.
Travel domestically and internationally based on program and CMO needs.

Requirements

M.S. or Ph.D. in synthetic organic chemistry.
Postgraduate experience in process chemistry and/or cGMP chemical manufacturing (2-3+ years for Ph.D., 5+ years for M.S.).
Working knowledge of chemical reaction mechanisms and kinetics.
Experience with process optimization and scale-up.
Familiarity with cGMP regulatory compliance in chemical manufacturing.
Experience preparing technical reports and presenting findings to technical and cross-functional audiences.
Ability to manage multiple projects and deadlines concurrently.
Availability to travel domestically and internationally.

Skills

ChemDraw
SciFinder

Location

South San Francisco

Work Type

Hybrid

Experience Level

2-3+ years for Ph.D.
5+ years for M.S.

Education Level

M.S. or Ph.D. in synthetic organic chemistry

Salary/Compensations

$158,000 - $193,000
Eligible for an annual performance bonus

Benefits

Competitive medical, dental, and vision insurance
Mental health offerings
Equity incentive plan
401(k) program with employer match
Generous holiday and PTO policy

About the Company

Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases.
Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease.
We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease.
Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases.
We are fostering a culture that encourages vision, initiative and the development of talent.
Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work.
While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.

Equal Opportunity

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.
Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
Stand True – Our integrity is foundational; it guides us no matter the obstacle.