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About the Role

Operates and supports advanced cryo-electron microscopy instrumentation within the Weill Cornell Medicine Cryo-EM Core Facility. This role offers opportunities to collaborate with investigators, providing scientific consultation, technical expertise, and access to state-of-the-art cryo-EM technologies.

Responsibilities

• Operates, maintains, and performs quality control of cryo-electron microscopy instrumentation.
• Performs cryo-EM and Cryo-ET sample preparation, specimen screening, automated data collection, and basic image quality assessment.
• Provides scientific and technical support to investigators utilizing Cryo-EM Core services.
• Assists with user training on core instrumentation and standard operating procedures.
• Maintains accurate records of instrument usage, maintenance activities, and experimental workflows.
• Maintains cryogenic sample inventories and storage systems.
• Assists with routine instrument maintenance and coordinates vendor service visits.
• Maintains laboratory supplies, consumables, and equipment inventories.
• Ensures compliance with institutional safety policies and laboratory procedures.
• Contributes to the development and optimization of core workflows and standard operating procedures.
• Participates in the testing and implementation of new technologies and methodologies.
• Works closely with investigators to understand project goals and recommend appropriate Cryo-EM workflows and instrumentation.

Requirements

• Experience with cryo-electron microscopy, cryo-electron tomography, transmission electron microscopy, or related structural biology techniques is preferred.
• Experience working in a shared resource laboratory or core facility is preferred.
• Previous Cryo-EM and/or Cryo-ET experience is a plus.
• Ability to interact effectively with investigators possessing diverse levels of microscopy experience.
• Ability to troubleshoot instrumentation and experimental workflows.
• Demonstrated organizational skills and ability to pay close attention to detail.
• Ability to work safely in a BSL1 and/or BSL2 environment.
• Work will be in both a laboratory and an office environment.

Skills

• Cryo-electron microscopy
• Cryo-electron tomography
• Transmission electron microscopy
• Structural biology techniques
• Microscopy
• Instrumentation troubleshooting
• Experimental workflow troubleshooting
• Communication skills
• Teaching skills
• Cooperative work
• Problem-solving
• Decision-making
• Organizational skills
• Attention to detail

Location

• Upper East Side

Work Type

• Full-time

Experience Level

• Senior

Education Level

• BS in related field

Salary/Compensations

• $83,100.00 - $100,500.00

About the Company

• Cornell welcomes students, faculty, and staff with diverse backgrounds from across the globe to pursue world-class education and career opportunities, to further the founding principle of “any person, any study.”

Equal Opportunity

• No person shall be denied employment on the basis of any legally protected status or subjected to prohibited discrimination involving, but not limited to, such factors as race, ethnic or national origin, citizenship and immigration status, color, sex, pregnancy or pregnancy-related conditions, age, creed, religion, actual or perceived disability (including persons associated with such a person), arrest and/or conviction record, military or veteran status, sexual orientation, gender expression and/or identity, an individual’s genetic information, domestic violence victim status, familial status, marital status, or any other characteristic protected by applicable federal, state, or local law.
• Cornell University embraces diversity in its workforce and seeks job candidates who will contribute to a climate that supports students, faculty, and staff of all identities and backgrounds.
• We hire based on merit, and encourage people from historically underrepresented and/or marginalized identities to apply.
• Consistent with federal law, Cornell engages in affirmative action in employment for qualified protected veterans as defined in the Vietnam Era Veterans’ Readjustment Assistance Act (VEVRRA) and qualified individuals with disabilities under Section 503 of the Rehabilitation Act.
• We also recognize a lawful preference in employment practices for Native Americans living on or near Indian reservations in accordance with applicable law.