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About the Role

AbbVie's MPDD organization is seeking a highly motivated, creative, and collaborative scientist with expertise in assay development, chemical automation, and integrated workflow design for an Associate Scientist I position. The primary role of this position will emphasize analytical chemistry, HPLC–mass spectrometry (HPLC–MS), laboratory automation, and implement automated and data-enabled workflows that accelerate decision-making and improve throughput in early development sciences.

Responsibilities

Utilize state of the art automation and computational tools supported by expertise in biopharmaceutics, drug delivery, and solid-state chemistry to collaboratively progress candidates with higher probability of success into development and advise clinical formulation strategy.
Identify the commercial solid form of the active pharmaceutical ingredient (API) and establish structure-property-performance correlations to help deliver robust commercial processes and align control strategies across drug substance and product.
Transition drug substance isolation processes and relevant physical characterization methods to commercial manufacturing sites and work within teams to ensure successful regulatory submissions.
Conduct developability assessment to select molecules with higher probability of success for clinical development and eventual commercialization.
Profile physicochemical properties, develop preclinical formulations, identify solutions to in vivo absorption challenges, and advance novel drug delivery strategies across multiple routes of administration.
Contribute to the profiling of physiochemical properties, screening and development of preclinical formulations, and the advancement of platform workflows for emerging modalities of interest.
Build and optimize integrated capabilities that support faster, data-driven, more efficient pipeline progression.
Design and implement efficient, reproducible, and scalable laboratory processes.

Requirements

Bachelor’s Degree or equivalent education with typically 5 years of experience, or Master’s Degree or equivalent education with typically two years of experience in pharmaceutical or related industry.
Familiarity and preferred hands-on experience in physicochemical property assessment related to understanding CMC developability profile and potential risk mitigation strategies.
Hands-on Experience with HPLC–MS, high-resolution mass spectrometry, or related analytical platforms.
Hands-on experience in assay development, automation, and workflow optimization.
Strong understanding of physiochemical property profiling and its application to early developability assessment, including methods relevant to solubility, stability, and other compound attributes that inform pipeline decisions.
Familiarity with preclinical formulation development and screening strategies, including support for enabling formulations for emerging or complex modalities.
Familiarity with analytical, biophysical, and in vitro techniques used to generate high-quality data for early development decision making.
Experience collaborating with data scientists, computational chemists, or informatics partners.
Excellent organizational skills, self-management, and attention to detail, with the ability to manage multiple priorities in a fast-paced environment.

Skills

Assay development
Chemical automation
Integrated workflow design
Analytical chemistry
HPLC–mass spectrometry (HPLC–MS)
Laboratory automation
Automated and data-enabled workflows
Physiochemical property profiling
Preclinical formulation screening
Platform workflows for emerging modalities
Plate-based optical spectroscopy
Liquid handler operation
Custom scientific programming and scripting
Machine learning and model-building concepts
High-performance liquid chromatography (HPLC)
Mass spectrometry
Powder X-ray diffraction (pXRD)
Optical microscopy
Light scattering techniques
Thermal analysis
Biophysical characterization techniques
Automated data capture
Laboratory instrumentation integration
Assay miniaturization
Data analysis workflows
High-resolution mass spectrometry
Workflow optimization
Solubility
Stability
Compound attributes
Enabling formulations for emerging or complex modalities
Analytical techniques
Biophysical techniques
In vitro techniques
Data interpretation

Experience Level

Associate Scientist I

Education Level

Bachelor’s Degree
Master’s Degree
Pharmaceutical Sciences
Pharmaceutical Engineering
Chemical/Biomedical Engineering
Chemistry
Materials Science

Salary/Compensations

USD 75000 - USD 142500 - yearly

Benefits

Paid time off (vacation, holidays, sick)
Medical/dental/vision insurance
401(k)
Eligible to participate in our short-term incentive programs

About the Company

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.
We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio.

Equal Opportunity

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.
Equal Opportunity Employer/Veterans/Disabled.