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About the Role

We are seeking a creative and highly motivated Research Associate to join our Discovery Biology team. You will work closely with members of the drug discovery team to conduct and oversee biological testing of new inhibitors.

Responsibilities

• Executing in vitro experiments to identify and characterize compounds with biological activity, specially viral infection inhibitors.
• Developing, optimizing, and validating biochemical and cell-based assays to support ongoing discovery projects.
• Making detailed observations, analyzing data, and interpreting results in collaboration with senior research members.
• Supporting multiple projects and learning new techniques for novel exploratory discovery work.
• Presenting experimental findings, assay results, and scientific rationale clearly to internal project teams.
• Utilizing data analysis software and MS Office applications.
• Managing compound inventories and assay data.
• Participating in general lab maintenance including reagent preparation, ordering of general lab supplies, and maintenance of equipment.

Requirements

• Minimum of two (2) years of relevant experience in industrial or academic settings, preference given to experience in a drug discovery setting.
• Must be comfortable working in a BSL2 setting with potentially infectious agents.
• Demonstrated expertise in ensuring good laboratory practices and BSL2 standards.
• Ability to clearly summarize and present experimental findings, data interpretation, troubleshooting outcomes, and scientific insights to support assay optimization and compound characterization.
• Motivated, and proactive cell biologist and/or molecular virologist with desire to work in a fast-paced, dynamic environment.
• Familiarity with Microsoft Office applications, molecular cloning programs, GraphPad Prism and scientific informatics tools for data input, analysis, and management.

Skills

• Assay development
• Cell biology
• Virology
• Molecular biology techniques
• Sterile technique
• Maintenance of mammalian cells
• Cytotoxicity assays
• Virus production and titration
• Transporter & reporter assays
• Antiviral activity assays & mechanism of action studies
• ELISA
• (RT)qPCR
• Molecular cloning
• Transfection
• Western blot
• Data analysis software
• MS Office applications
• GraphPad Prism
• Scientific informatics tools

Location

• On-Site, South San Francisco, CA

Work Type

• Regular, Full-time, Exempt

Experience Level

• Minimum of two (2) years of relevant experience

Education Level

• Sc./M.S. or equivalent degree in Cell Biology, Molecular Biology, Virology, or relevant scientific discipline

Salary/Compensations

• $87,000 - $91,260 annualized

About the Company

• Assembly Bio (NASDAQ: ASMB) is an ambitious biopharmaceutical company with cutting-edge therapeutic candidates capable of improving the lives of millions living with devastating viral and liver diseases.
• We have multiple ongoing clinical programs focused on the development of novel treatments for herpesviruses, hepatitis delta virus (HDV), cholestatic liver diseases and hepatitis B virus (HBV).
• Our research organization is dedicated to the discovery of new therapies to change the treatment paradigm for individuals living with serious viral and liver diseases.
• We pride ourselves on creating a culture and work environment that is scientifically driven, ambitious, and collaborative.
• We encourage diversity of thought that leads to great innovation and are looking to add great people to our dynamic team who are driven to transform the lives of patients.
• We set our sights high—and pursue our goals with determination.
• Our unique organization stands ready to welcome talented, motivated individuals, who share our ambitions.

Equal Opportunity

• As an equal opportunity employer, we are committed to diversity and inclusion and will not tolerate discrimination and harassment of any kind.
• All employment decisions are based on business needs, job requirements and individual qualifications, without regard to race, color, religion or belief, national, social or ethnic origin, sex (including pregnancy), age, physical, mental or sensory disability, HIV status, sexual orientation, gender identity and/or expression, marital, civil union or domestic partnership status, past or present military service, family medical history or genetic information, family or parental status, or any other status protected by the laws or regulations in the locations where we operate.