Impress employers and recruiters.
Choose from hundreds of resume examples.

Impress employers and recruiters.
Choose from hundreds of resume examples.

Target Resume Now

About the Role

This role is for a senior industry scientist responsible for delivering antibody programs for customers, with a focus on CHO cell-line development and upstream process development. The position involves owning the scientific delivery of customer programs, defining development plans, designing experiments, interpreting data, and communicating results.

Responsibilities

• Owning the scientific delivery of customer antibody programs from cell-line strategy through media and feed development, bioreactor confirmation and a clear scale-up package.
• Designing and driving CHO cell-line development: host and vector choices, transfection, pool generation, clone selection, screening, stability assessment and cell-banking strategy.
• Developing and optimising basal media and feeds using disciplined, decision-oriented experiments grounded in cell metabolism and process biology.
• Translating customer goals, target product profiles and timelines into development plans with clear milestones, risks, decision gates and data packages.
• Designing DoEs and run plans across high-throughput screens, 300 mL bioreactors and 3 L confirmation runs; setting parameters, sampling plans and analytical requirements.
• Diagnosing the causes of weak growth, viability, productivity or product quality - separating cell-line, media, feed and process effects and choosing the next experiment quickly.
• Working closely with analytics and downstream teams so upstream decisions reflect titre, product quality, impurity burden and the needs of the complete manufacturing process.
• Communicating directly and credibly with customers: explaining results, trade-offs, uncertainty and the recommended path forward in clear scientific and commercial language.
• Delegating routine execution to operations technicians while staying close enough to the work to protect scientific quality and stepping in hands-on when the biology demands it.
• Turning lessons from individual programs into reusable platform rules, operating windows and better development workflows.

Requirements

• At least five years of relevant industry experience required in addition to the PhD.
• Delivered mammalian cell-culture or antibody-development programs in a biotechnology or biopharmaceutical setting; academic experience alone is not sufficient.
• A track record of personally taking antibody-producing CHO cell lines from transfection or pool generation through clone selection, stability assessment, productivity optimisation and banking.
• Substantial experience developing or optimising cell culture processes.
• A record of designing rigorous experiments and making sound decisions from incomplete data across multiple concurrent development programs.
• Experience owning program outcomes and communicating directly with internal or external customers, not only completing an assigned scientific work package.
• Strong written and verbal communication skills.
• High pace, high ownership and low ego; comfortable being accountable for delivery in a small team and remaining hands-on when needed.

Skills

• CHO cell-line development
• Upstream process development
• Antibody program delivery
• Cell metabolism
• Process biology
• Experimental design
• Bioreactor operation
• Data interpretation
• Customer communication
• Biologics analytics literacy (titre, metabolites, glycosylation, charge variants, aggregation, HCP and DNA)
• Scale-up
• Technology transfer
• CMC
• GMP
• Regulatory-development

Location

• Alexandria, Sydney, Australia

Work Type

• Full-time

Experience Level

• Senior

Education Level

• PhD in cell biology, molecular biology, biochemistry, biotechnology, bioprocess engineering or a closely related field

About the Company

• Airtree is advertising this role on behalf of one of our portfolio companies, who are currently in stealth mode.
• We exist to drastically increase access to advanced medicines.
• Small team, fast cycles, flat.
• Our seed round is closed, so we’re building now.