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About the Role

This Staff-level role owns the reliability, performance, security, and integrity of the analytical data platform (Mystra) and its agentic layer (MystraAI) end-to-end, setting the technical direction for other teams. You will lead the analytical data platform and Data-as-a-Service offering, shape the data foundations behind MystraAI, and line-manage a small team of engineers while remaining deeply hands-on. This role is ideal for someone who wants their work to sit at the intersection of large-scale infrastructure and meaningful science.

Responsibilities

Architect, tune, and operate multi-tenant ClickHouse or equivalent OLAP database clusters at multi-trillion-row, petabyte scale.
Own SLOs, observability, capacity planning, and incident response for data-intensive systems and pipelines.
Shape Data-as-a-Service as a real product, including a secure, multi-tenant, immutable release architecture.
Scale the data foundations behind MystraAI and own secure, tenant-scoped access for agents.
Treat security as a first-class architectural concern, focusing on tenant isolation, secrets management, and least-privilege access.
Set technical direction, mentor, and line-manage a small team of engineers.
Influence decisions well beyond your own team.

Requirements

Recognised specialist who leads through expertise with principal-level individual-contributor depth.
Deep experience designing and tuning multi-tenant ClickHouse at extreme scale.
Experience with SRE discipline (SLOs, observability, capacity planning, incident response) for analytical data systems and pipelines.
Experience productizing Data-as-a-Service, considering secure, multi-tenant, immutable releases, and discoverability.
Understanding of exposing platform data to agents safely and at scale, including access patterns, tenant isolation, and guardrails.
Experience designing for multi-tenant security, including isolation, least-privilege access, and secrets management.
Experience driving technical direction and innovation across a platform.
Experience mentoring engineers.
Experience line-managing a small team without losing hands-on edge.

Skills

Large-scale OLAP / ClickHouse
Reliability engineering for data platforms
Data-as-a-Service productisation
Agent-ready data infrastructure
Multi-tenant security
Technical leadership
Mentoring
Line management

Location

Oxford (Hybrid)
London (Hybrid)

Work Type

Hybrid Working

Experience Level

Staff-level
Principal-level

Salary/Compensations

Competitive Salary: Salaries are externally benchmarked annually to ensure top-of-market compensation.

Benefits

Clear Career Path: A straightforward, open progression framework.
Continuous Learning: Including external courses and a wide library of L&D materials.
Holiday: 25 days annual leave, plus bank holidays, plus an extra 3-day company-wide shutdown at year-end.
Financial & Health Security: Market-leading pension scheme, comprehensive private health insurance with NO excess, critical illness, and life assurance.
Enhanced Leave: Enhanced paid family leave.
Flexible Working: Hybrid Working.
Truly Inclusive Time Off: 'Bank Your Bank Holiday' program.
Vibrant Social Culture: Regular Town Halls, team picnics, organised sports events.
Green Commute: Cycle-to-Work scheme.

About the Company

Genomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare.
Our united vision is to help people live longer healthier lives, using the power of genomics.
We aim to help people live longer, healthier lives by super-charging drug discovery and development for novel treatments with our AI-enabled advanced genetic analytics platform.
We also help people understand their personal risk of common chronic diseases through polygenic risk scores, giving doctors and health systems the chance to get the right people into the right prevention, screening and treatment programmes at the right time.

Equal Opportunity

We are dedicated to creating a diverse environment and are proud to be an equal-opportunity employer.
All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.