Impress employers and recruiters.
Choose from hundreds of resume examples.

Impress employers and recruiters.
Choose from hundreds of resume examples.

Target Resume Now

About the Role

This is a hands-on, bench-focused role where you will produce RNA reagents and run cell-based assays to evaluate their performance. The ideal candidate is a versatile experimentalist skilled in in vitro transcription (IVT), mammalian cell culture, and end-to-end cell-based assays. You will collaborate with cross-functional teams to drive the company's core experimental engine.

Responsibilities

• Produce research-grade RNA by in vitro transcription (IVT) at routine cadence and scale, including template preparation, transcription, capping and tailing, DNase treatment, and purification.
• Release RNA material against defined quality specifications.
• Perform RNA quality control (concentration, purity, and integrity) using spectrophotometry, fluorometry, and electrophoretic/capillary methods.
• Maintain mammalian cell lines and disease-relevant models, ensuring assay-ready cells are available on schedule.
• Deliver PRINT RNA into cells via transfection, lipofection, and electroporation/nucleofection across multiple cell types.
• Execute readout assays including reporter assays, ELISA, qPCR/ddPCR, flow cytometry, and high-content imaging.
• Analyze, plot, and document results clearly in the electronic lab notebook, flagging anomalies and contributing to troubleshooting.
• Support assay optimization and modest throughput scale-up, including work with liquid-handling automation.
• Assist with lab operations, including reagent and consumable inventory, sample and reagent tracking, and instrument upkeep.

Requirements

• Bachelor's or Master's degree in molecular biology, biochemistry, cell biology, biotechnology, or a related field.
• Approximately 2–5 years of hands-on laboratory experience, with industry experience preferred.
• Strong, current mammalian cell culture skills, including sterile technique, maintenance of multiple cell lines, and transfection.
• Hands-on molecular biology experience, including RNA handling and RNase-free technique.
• Demonstrated reliability, organization, and attention to detail, producing reproducible data and documenting it clearly.
• Ability to manage multiple concurrent tasks in a fast-paced environment.
• Ability to communicate results to a cross-functional team.

Skills

• In vitro transcription (IVT)
• Mammalian cell culture
• Cell-based assays
• RNA handling
• RNase-free technique
• Reporter assays
• ELISA
• qPCR/ddPCR
• Flow cytometry
• High-content imaging
• Spectrophotometry
• Fluorometry
• Electrophoretic/capillary methods
• Transfection
• Lipofection
• Electroporation/nucleofection
• Electronic lab notebook
• Liquid-handling automation
• Automated liquid handling (e.g., Biomek, Echo)
• High-throughput assay workflows
• Secreted-protein or hormone assays
• Gene therapy
• mRNA
• RNA-based therapeutic modalities
• Data analysis in R, Python, GraphPad Prism, or similar

Location

• South San Francisco

Work Type

• Full-time
• Onsite

Experience Level

• Research Associate
• Senior Research Associate
• 2-5 years

Education Level

• Bachelor's degree
• Master's degree

Salary/Compensations

• $98,000–$130,000

Benefits

• Bonus eligibility
• Equity incentives
• Benefits

About the Company

• Addition Therapeutics is at the forefront of biotechnology innovation, building the next generation of gene therapy using our proprietary PRINT™ (Precise RNA-mediated Insertion of Transgenes) platform.
• Our PRINT™ platform redefines genetic medicine by enabling the development of RNA-only therapeutics capable of inserting any genetic element into specific safe harbor sites within the genome.
• We are a Series A-stage company advancing programs across rare and common diseases.

Equal Opportunity

• Addition Therapeutics is an equal opportunity employer.
• We value diverse perspectives and are committed to building an inclusive team.