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About the Role

The Director, Project Management Office (PMO) leads the PMO function for the Syracuse Bio Campus, ensuring effective portfolio governance, project execution, and cross-functional alignment for client programs and internal initiatives. This role establishes and drives PMO operating standards, governance processes, performance metrics, and execution disciplines to enable visibility, predictability, and delivery excellence across the project portfolio. As a senior leader, this role translates site and business priorities into PMO strategy and frameworks that support operational performance, client satisfaction, and business growth, serving as a strategic business partner to site leadership and a senior point of contact for clients.

Responsibilities

Lead the PMO function for the Syracuse Bio Campus, including functional priorities, governance standards, operating mechanisms, and talent development.
Translate site, functional, and business objectives into PMO strategies, priorities, and execution frameworks.
Partner with the VP, Global PMO to align site PMO objectives with global PMO strategy, governance standards, reporting expectations, and continuous improvement priorities.
Establish and sustain PMO frameworks, processes, tools, and performance measures.
Serve as a strategic partner to site leadership, helping to identify risks, opportunities, resource needs, and operational tradeoffs.
Influence and help shape PMO best practices across the broader global network.
Provide leadership and oversight for the execution of Syracuse client projects and key internal initiatives.
Direct portfolio governance processes, including project reviews, milestone assessments, escalation management, portfolio reporting, and decision-support mechanisms.
Ensure risk management, issue escalation, and mitigation planning are embedded within project execution.
Drive portfolio visibility through clear governance, KPI reporting, lessons learned, and performance reviews.
Lead PMO engagement in the planning and execution of complex client-facing programs, including end-to-end CDMO projects.
Identify and implement improvements to PMO effectiveness.
Serve as a senior PMO representative and trusted liaison for client stakeholders.
Lead or participate in Joint Steering Committee (JSC) meetings and other governance forums with clients.
Partner closely with Business Development, Development, and Operations to support new business opportunities, project onboarding, technical transfers, change controls, and ongoing client program success.
Ensure project scope, change order management, and program communications are managed effectively.
Support business growth by helping to create delivery models, governance approaches, and cross-functional plans.
Lead PMO financial oversight for client programs and the function, including forecasting, budget management, invoicing alignment, change impact visibility, and cost control.
Provide site and senior leadership with clear visibility to project financials, milestones, risks, constraints, and operational implications.
Partner with site leadership and cross-functional stakeholders on strategic capacity planning, prioritization, and resource allocation.
Drive operational discipline and accountability across the PMO.
Support the resolution of highly complex project and portfolio challenges.
Lead, develop, and coach a team of project managers responsible for client project execution.
Set clear expectations, performance standards, and development priorities for the PMO team.
Build PMO organizational capability through mentoring, succession planning, knowledge sharing, and continuous professional development.
Foster a high-performing team culture grounded in collaboration, inclusion, ownership, client focus, and continuous improvement.
Lead through both direct people management and matrix influence to align teams, resolve conflict, and drive execution.

Requirements

Bachelor’s degree in Engineering, Life Sciences, Business, or a related field required; advanced degree preferred.
12+ years of relevant experience, including significant experience in the biopharma and/or CDMO industry.
Significant leadership experience in project management, program/alliance management, PMO leadership, and/or related operational leadership roles supporting complex biologics programs.
Demonstrated success leading complex cGMP manufacturing, technical transfer, and/or end-to-end client programs within a contract development and manufacturing environment.
Proven experience establishing, leading, or enhancing PMO governance frameworks, portfolio management processes, and performance reporting mechanisms.
Experience leading direct reports and developing talent within a matrixed, cross-functional organization.
Demonstrated success influencing senior leaders, clients, and cross-functional stakeholders to drive decisions, alignment, and business outcomes.
Strong experience managing client relationships, governance forums, and complex project communications at a strategic level.
PMP (Project Management Professional) or equivalent certification preferred.
Deep knowledge of project and portfolio management methodologies, risk management practices, and governance models within a biopharmaceutical or CDMO environment.
Strong understanding of biologics manufacturing, process and analytical technical transfer, cGMP operations, and regulatory requirements in GxP settings.
Strong business and financial acumen, including understanding of project forecasting, cost management, invoicing processes, change impact assessment, and client financial visibility.
Ability to translate business strategy and operational priorities into PMO governance, execution plans, and measurable outcomes.
Demonstrated ability to influence senior leaders, clients, and cross-functional stakeholders across a matrixed organization.
Strong people leadership skills, including coaching, performance management, organizational development, and capability building.
Ability to lead through ambiguity, manage competing priorities, and drive resolution of complex operational and portfolio issues.
Excellent communication, presentation, negotiation, and stakeholder management skills, including executive-level communication.
Proficiency with Microsoft Project, Smartsheet, Power BI, and other project and portfolio management tools.
Ability to balance strategic leadership with appropriate operational involvement.
Prolonged periods of sitting or standing at a desk, participating in meetings, and working on a computer.
Frequent use of standard office equipment.
Occasional movement throughout the site to attend meetings or interface with operations teams.
Ability to wear required personal protective equipment (PPE) when entering controlled manufacturing or lab environments.
Visual acuity to review project data, timelines, and technical documentation.
Occasional lifting or carrying of materials (up to 15 lbs.).

Skills

Project Management
Portfolio Management
Risk Management
Governance Frameworks
Biologics Manufacturing
Technical Transfer
cGMP Operations
Financial Acumen
Stakeholder Management
People Leadership
Coaching
Performance Management
Organizational Development
Microsoft Project
Smartsheet
Power BI

Location

East Syracuse, NY

Work Type

Onsite
Full-time

Experience Level

Director
Senior Leader

Education Level

Bachelor's degree in Engineering, Life Sciences, Business, or a related field
Advanced degree preferred

Salary/Compensations

$155,000—$214,000 USD

Benefits

Target Bonus 23%

About the Company

We are LOTTE BIOLOGICS! Delivering Therapies That Enable a Healthier World.
A new company, built on 80 years of tradition.
We embody our core values of being Inspired by Science, Embracing Diversity, Fostering Talent, and Connecting Lives.
Our mission is to be the most trusted partner in the industry, with high standards of quality and continuous innovation, to reliably deliver benefits for patients worldwide.

Equal Opportunity

We are an Equal Employment Opportunity (“EEO”) Employer.
We believe that women, people of color, veterans and LGBTQ communities must participate in the work we do, so we strongly encourage applications from people with these identities or who are members of underrepresented communities!
If this is the work that you want to do, in a culture of inclusion and excellence with the goal of making our world to be a healthier place, then please apply today!