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About the Role

We are looking for a talented and versatile Scientist I to join Discovery Science at Altos Labs. Our team uses functional genomics to unravel the deep biology of cellular rejuvenation and to restore cell health and resilience. In this role you will develop physiologically relevant in vitro and ex vivo disease models and integrate these with in vivo studies to identify interventions that reverse disease-associated cell states.

Responsibilities

Design and execute innovative research strategies to identify causal regulators of cell state, aging, regeneration, and disease biology.
Develop, benchmark, and validate disease cell models of age-related and disease-associated cell states.
Scale assays to screen candidate interventions across cell models, and contribute to data-driven prioritization decisions on which candidates and which models to advance.
Design, conduct, and interpret in vivo studies to evaluate candidate interventions and benchmark disease models against in vitro findings.
Elucidate the mechanisms of action underlying promising interventions to identify and prioritize therapeutic targets and modalities.
Support and manage internal/external collaborations across one or more multidisciplinary projects to accelerate essential research activities.
Develop project-specific experimental strategies, techniques, and procedures.
Collaborate closely with other scientists and cross-functional teams to integrate multidimensional datasets and generate actionable biological insight.
Contribute to the writing and dissemination of research results.

Requirements

PhD in Biology, Cell Biology, Physiology, or a related field, with 0-3 years of post-PhD experience.
Proven track record of elucidating complex age-associated disease mechanisms, including but not limited to kidney, lung, liver and skin indications.
Experience developing and validating cell-based disease assays, including benchmarking assay performance.
Strong hands-on experience conceptualizing and performing rodent in vivo disease assays, with a background in relevant laboratory techniques and methods.
Excellent professional writing skills and the ability to communicate through writing and presentations to a variety of audiences.
Problem-solving skills sufficient to identify issues, conduct research, and develop innovative solutions.
Ability to maintain cooperative working relationships with a broad range of people.
Demonstrated high productivity and ability to complete work in a timely manner.
Ability to organize work and set priorities.
Ability to focus on details to produce accurate, quality work driven by deadlines.
Ability to work in a dynamic environment and with others in a team.
Strengths in dealing with ambiguity.

Skills

Functional genomics
In vitro disease models
Ex vivo disease models
In vivo studies
Molecular biology
Cell biology
Disease biology
In vitro disease assays
In vivo disease assays
Aging biology
Regeneration
Fibrosis
Inflammation
Metabolic disease
Neurodegeneration
Mechanisms of action
High-throughput screening
Functional genomics assays
Chronic disease models
Computational biology
Bioinformatics

Location

Redwood City, California

Work Type

Full-time

Experience Level

0-3 years of post-PhD experience

Education Level

PhD in Biology, Cell Biology, Physiology, or a related field

Salary/Compensations

$134,700 - $172,700

Benefits

Collaboration
Scientific excellence
Belonging
Inclusive environment

About the Company

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.
Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list.
At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission.

Equal Opportunity

Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
Altos prohibits unlawful discrimination and harassment.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.