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About the Role

Axiom is building an ecosystem to compound technology that will replace animal testing and reshape clinical trials. We partner with various entities to convert capital into data and machine learning models, deploying them within pharmaceutical companies to enhance drug development processes. Our focus is on understanding drug discovery needs, building datasets, advancing ML research, and collaborating with AI labs to improve model reasoning capabilities. This creates a compounding loop where customer understanding drives data generation, better data enhances models and infrastructure, stronger models expand offerings, and these capabilities are deployed into pharma workflows to solve high-value drug discovery problems. Currently, we are addressing drug-induced liver injury with an integrated data and agentic system used by leading pharma and biotech companies. Axiom plans to invest significantly in large human datasets across organ systems, paired with an agentic harness for superior prediction of human drug outcomes.

Responsibilities

Own the commercial strategy and operations.
Map the people and phased progression strategy for every major account, including top pharmaceuticals and AI research labs.
Own pilot operational execution and pilot-to-revenue conversion across Axiom’s commercial pipeline.
Partner closely with the CEO and technical leadership to translate customer excitement into durable enterprise adoption for companies of all sizes.
Chart the course for major accounts, guiding them from six figures to eight figures and beyond.
Build relationships across scientific, technical, business, legal, procurement, and executive teams.
Build and run a rigorous commercial operating system, including pipeline management, forecasting, pricing, packaging, deal strategy, and expansion.
Act as the voice of the customer within Axiom, bringing field insights back into product, roadmap, and company direction.
Drive creative dealmaking across SaaS, platform licenses, strategic research collaborations, drug discovery partnerships, and data relationships.
Partner with the CEO as a true counterpart, shaping strategy, refining company direction, and driving decisions through high conviction and intense debate.
Be deeply present in person, in the office, with customers, and at conferences to build relationships and drive customer outcomes.
Handle operational tasks by pushing deals through legal, procurement, and IT, while ensuring flawless execution by the Axiom team.
Help ensure internal operations run smoothly across high-priority customer and company initiatives.

Requirements

A world-class operator with a strong commercial, operations, and strategy background.
Proven track record of driving complex enterprise relationships to real revenue.
Deep understanding of pharma and biotech, including discovery workflows, toxicology, DMPK, and how large organizations evaluate and adopt new platforms.
Exceptional customer management, commercial strategy, and internal coordination/operations skills.
Works extremely hard and integrates work into their identity.
Strong product instinct and customer empathy, with the ability to translate customer needs back into the company.
Deep, innate curiosity for science and software.
Highly intelligent, energetic, persuasive, and ambitious.
Able to converse with successful drug hunters and AI researchers.
Strong technical aptitude, capable of discussing AI, scientific product vision, and business strategy credibly.
Creative dealmaker skilled in structuring non-obvious partnerships and closing difficult deals.
Strong operator capable of introducing rigor, accountability, and clarity without bureaucracy.
Comfortable challenging the CEO and leadership team with well-reasoned opinions.
Thrives in an intense, high-expectation, in-person, honest, and blunt environment.
Based in San Francisco, with regular travel to customers and conferences.

Skills

Commercial strategy
Operations
Strategy
Enterprise relationship management
Customer management
Internal coordination
Pipeline management
Forecasting
Pricing
Packaging
Deal strategy
Expansion
Creative dealmaking
SaaS
Platform licenses
Research collaborations
Drug discovery partnerships
Data relationships
AI
Scientific product vision
Business strategy

Location

San Francisco

Work Type

In-person
Full-time

Experience Level

Senior

About the Company

Axiom is building an ecosystem to compound technology which will replace animal testing and, over time, reshape how clinical trials are run.
We work with many different partners to turn capital into data and machine learned models then deploy those models into the largest pharmaceutical companies in the world to improve how medicines are developed.
It starts with deeply understanding the needs of drug hunters inside large pharma, especially around drug toxicity and safety.
Those needs shape the world-class datasets we build from scratch.
We then use that data to advance our own ML research, while also collaborating with leading AI labs to improve frontier models’ ability to reason over Axiom’s data inside Axiom’s agent harness.
This creates a compounding loop: deeper customer understanding shapes the data we generate; better data improves frontier models, Axiom’s fine-tuned models, and our agentic infrastructure; stronger models and tooling expand the capabilities we can offer; and those capabilities are forward deployed into pharma's drug discovery workflows, where scientists use them to solve the highest value drug discovery problems.
In turn, this helps us identify the next problems to tackle.
Today, we are focused on solving drug-induced liver injury through an integrated data and agentic system already being used by 7 of the top 20 pharma companies and several of the world’s most innovative biotechs.
Over time, Axiom will invest billions into the world’s largest human datasets across all the major organ systems, paired with an agentic harness that uses this data to predict human drug outcomes dramatically better than animals and phase 1 clinical trials.