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About the Role

Dr. Abid Hussaini's lab at the Nathan Kline Institute is seeking a Postdoctoral Research Scientist to investigate the neurobiology of Alzheimer's disease (AD) using mouse models. The role involves studying how amyloid beta (Aβ) and tau pathology lead to neuronal network dysfunction and cognitive deficits using systems neuroscience approaches like in vivo electrophysiology, optogenetics, chemogenetics, and behavioral testing. This fully supported position is for up to 3 years by NIH grants.

Responsibilities

Design and lead an independent research project on Alzheimer's disease in mouse models, focusing on in vivo electrophysiology, optogenetics, and chemogenetics techniques.
Plan, execute, and analyze complex experiments involving stereotaxic surgeries, electrode implantation, and behavioral testing.
Analyze and interpret large-scale data from in vivo electrophysiology and behavioral experiments, collaborating with computational neuroscientists on advanced neural data analysis.
Develop and optimize new experimental protocols as needed, maintaining detailed records of experiments, analyses, and results.
Present research findings at lab meetings, scientific conferences, and seminars.
Prepare and publish high-quality manuscripts in peer-reviewed journals.
Contribute to grant writing and funding applications.
Stay current with the latest developments in AD research and neuroscience techniques.
Mentor and supervise junior lab members, including graduate students and research technicians.

Requirements

Bachelor's degree and two years of professional research experience in an appropriate field or master's degree in an appropriate field may substitute for one year of experience.
Expertise in electrophysiology techniques (preferably in vivo) and proficient in rodent surgeries.
Track record of writing and publishing research articles in peer-reviewed journals.
Solid understanding of experimental design, data analysis, and statistical methods.
Excellent written and verbal communication skills in English.
Ability to work independently and as part of a collaborative team.
In-depth knowledge of systems neuroscience and Alzheimer's disease literature.
Experience in neurodegenerative disease research, particularly Alzheimer's disease.
Hands-on experience with optogenetics and chemogenetics.
Expertise in performing stereotaxic injections and implanting electrodes for in vivo recordings.
Proficiency in data analysis programming languages (e.g., MATLAB, Python, R).
Experience mentoring junior researchers or students.
Prospective appointees will be checked against the Staff Exclusion List (SEL) maintained by the Justice Center for the Protection of People with Special Needs.
Prospective employees whose names appear on the SEL as having been found responsible for serious or repeated acts of abuse or neglect will be barred from appointment.
Prospective employees will be screened against the Statewide Central Register of Child Abuse and Maltreatment (SCR).
Prospective employees whose names are indicated on the SCR may be barred from appointment.

Skills

In vivo electrophysiology
Optogenetics
Chemogenetics
Behavioral testing
Stereotaxic surgeries
Electrode implantation
Neural data analysis
Experimental protocol development
Grant writing
MATLAB
Python
R

Location

Orangeburg, NY

Work Type

Fully supported
Full-time

Experience Level

Postdoctoral

Education Level

Bachelor's degree
Master's degree

Salary/Compensations

Competitive salary

Benefits

Excellent Benefits Package

About the Company

The Nathan Kline Institute is a research facility focused on neurobiology.
The Research Foundation is a private not-for-profit corporation and is not an agency or instrumentality of the State of New York.
Employees of the Research Foundation are not state employees, do not participate in any state retirement system, and do not receive state fringe benefits.

Equal Opportunity

Affirmative Action/Equal Opportunity Employer - Disabled/Veteran, 41 CFR 60-741.5(a) and 41 CFR 60-300.5(a) compliant.