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About the Role

As a Staff Application Database Architect, you will be the backend database expert behind the production applications and web services that power Heartflow's clinical and operational platform. This is a hands-on role focused on designing OLTP schemas, writing and tuning high-performance queries, and working directly within Python/Django services. You will also set the architectural direction for data structure, access, and governance across our AWS-based platform. Exposure to Data Lake, analytics pipelines, or AI-enablement work is a plus.

Responsibilities

Design, build, and own OLTP database systems, including schema design, query optimization, and performance improvements for high-throughput, low-latency web services.
Define and implement best practices for database interaction within Python/Django services, addressing issues like N+1 queries and connection pool exhaustion.
Set direction for database operations, including uptime, capacity, backups, recovery, schema evolution, and incident response.
Own conceptual, logical, and physical data models for operational systems, ensuring consistent representation of clinical and operational data.
Contribute to enriching the transactional data model with semantics for AI agents and downstream consumers.
Ensure data architectures, flows, and access controls adhere to FDA, HIPAA, GDPR, and other applicable standards.
Support the Data Lake & Analytics Handoff by ensuring OLTP source systems produce well-modeled data for downstream pipelines.
Advance the Semantic Structure for AI Agent Context by contributing to the transactional data model with semantics.

Requirements

Deep, hands-on expertise in relational databases (PostgreSQL, MySQL, Aurora, or equivalent) supporting production web applications.
Strong experience building backend data layers for web applications and services in Python, with expert-level fluency in SQLAlchemy and/or the Django ORM.
Expert-level conceptual, logical, and physical modeling for transactional/OLTP workloads.
Experience with database engineering and DBA leadership, including performance tuning, partitioning, indexing strategy, replication, HA/DR, and operational excellence.
Experience building data systems in modern cloud ecosystems, with AWS preferred.
Experience working with clinical, imaging, or device data under regulatory regimes such as FDA, HIPAA, and GDPR.
Technical leadership experience, including mentoring senior engineers and driving cross-team architectural decisions.
Familiarity with Data Lake or lakehouse concepts is a plus.
Exposure to metadata, schema registries, ontologies, or semantic layers is a plus.

Skills

OLTP Database Engineering
Relational Databases (PostgreSQL, MySQL, Aurora)
Schema Design
Query Optimization
Indexing
Partitioning
Replication
HA/DR
Application & Web Service Data Access
Python
SQLAlchemy
Django ORM
Connection Pooling
Caching (Redis/Memcached)
Transaction Management
Data Modeling
Database Engineering
DBA Leadership
Cloud Platforms (AWS preferred)
RDS/Aurora
ElastiCache
Healthcare Data & Compliance (FDA, HIPAA, GDPR)
FHIR
HL7
DICOM
Technical Leadership
Mentoring
Architectural Decisions
Engineering Standards
Data Lake Concepts
Spark
Airflow
AI Enablement
Semantic Data

Location

Hybrid

Work Type

Hybrid

Experience Level

10+ years of relevant industry experience
Staff level

Education Level

Bachelor's degree in Computer Science, Engineering, or a related discipline, or equivalent experience
Master's preferred

Salary/Compensations

$190,000 to $250,000

Benefits

Bonus
Equity

About the Company

Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease using cutting-edge technology.
The flagship product is an AI-driven, non-invasive cardiac test called the Heartflow FFRCT Analysis.
Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway.
Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation.
The product is cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 500,000 patients worldwide.

Equal Opportunity

Heartflow is an Equal Opportunity Employer.
We are committed to a work environment that supports, inspires, and respects all individuals and do not discriminate against any employee or applicant because of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
This policy applies to every aspect of employment at Heartflow, including recruitment, hiring, training, relocation, promotion, and termination.