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About the Role
The Anacker lab at the New York State Psychiatric Institute (NYSPI) is seeking a highly motivated, independent postdoctoral researcher to investigate neural circuits underlying vulnerability and resilience to stress using in vivo brain imaging techniques in rodent models.
Responsibilities
- Perform stereotaxic surgeries for virus injection and fiber implantation into the mouse brain.
- Conduct mouse behavioral experiments using tasks of fear generalization and cognitive flexibility.
- Perform optogenetic and chemogenetic manipulation of neural circuits in freely moving mice.
- Conduct in vivo Ca2+ imaging of neural activity and neurotransmitter release in the mouse brain during behavior tasks.
- Maintain transgenic mouse colonies and perform genotyping.
- Perform immunohistochemistry and fluorescent microscopy.
- Independently conduct daily tasks and analyze in vivo imaging data using advanced tools in MATLAB or Python.
- Contribute to project development, including conceptual framing, conducting experiments, analyzing data, presenting findings at conferences, and publishing in scientific journals.
Requirements
- PhD in neuroscience or related field.
- At least two years of experience working with rodents.
- High level of motivation and organization.
- Experience with rodent behavior tasks.
- Experience with stereotaxic surgeries for virus injections and/or fiber implantations into the mouse brain.
- Analytic skills using basic statistical software (SPSS, R, GraphPad).
- Knowledge of MATLAB or Python.
Skills
- In vivo brain imaging techniques
- Rodent models
- Circuit tracing techniques
- Optogenetics
- Chemogenetics (DREADDs)
- In vivo Ca2+ imaging
- Biosensors
- Fear generalization tasks
- Cognitive flexibility tasks
- MATLAB
- Python
- Stereotaxic surgeries
- Immunohistochemistry
- Fluorescent microscopy
- Data analysis
- SPSS
- R
- GraphPad
Location
- 1051 Riverside Drive, New York, NY 10032
Work Type
- Full-time
Experience Level
- Postdoctoral
- 2+ years of experience working with rodents
- 1+ year of experience using optogenetic or in vivo imaging techniques in rodent brain
Education Level
- PhD in neuroscience or related field
Salary/Compensations
- $66,227-$75,827
Benefits
- Excellent Benefits Package
About the Company
- The Research Foundation for Mental Hygiene, Inc. (RFMH) promotes the mental health of all New Yorkers, focusing on providing hope and supporting recovery for adults with serious mental illness and children with serious emotional disturbances.
- RFMH is deeply committed to supporting underserved individuals, organizations, and communities.
- RFMH is focused on implementing activities and initiatives to reduce disparities in access, quality, and treatment outcomes for underserved populations.
- The researcher will be embedded in a highly collegial and collaborative environment in the Department of Psychiatry at Columbia University and the New York State Psychiatric Institute (NYSPI).
- The Research Foundation is a private not-for-profit corporation and is not an agency or instrumentality of the State of New York.
- Employees of the Research Foundation are not state employees, do not participate in any state retirement system, and do not receive state fringe benefits.
Equal Opportunity
- Applicants with lived mental health experience are encouraged to apply.
- RFMH is an equal opportunity/affirmative action employer.
- Affirmative Action/Equal Opportunity Employer - Disabled/Veteran, 41 CFR 60-741.5(a) and 41 CFR 60-300.5(a) compliant.