About the Role
This position offers hands-on training across multiple techniques (EM tissue processing and image reconstructions, light microscopy, and animal behavior) and the opportunity to contribute to ongoing publications and grant-funded projects. The candidate will assist with wet lab experiments and general lab maintenance, support animal behavior experiments, and perform serial section electron microscopy-based 3D reconstruction of neural circuits.
Responsibilities
- Perform serial-section electron microscopy-based 3D reconstruction and synaptic/circuit annotation of neural tissue using PyReconstruct.
- Execute rodent behavior experiments, and maintain associated husbandry, protocols, and data records.
- Perform light microscopy-based labeling and imaging, including immunohistochemistry, fluorescence in situ hybridization, and super-resolution (dSTORM) microscopy, to characterize synaptic and cell-type-specific molecular markers, in some cases correlated with electron microscopy datasets.
- Perform statistical analysis and data visualization (Python/R) of behavioral and imaging data, and assist with training and mentoring undergraduate researchers.
Requirements
- Bachelor's degree in Neuroscience, Biology, or a related field.
- Experience with serial-section electron microscopy-based 3D reconstruction software (e.g., PyReconstruct) preferred.
- Experience conducting animal behavior research.
- Proficiency in Python and/or R for statistical analysis and data visualization.
- One or more years of laboratory research experience (undergraduate research experience is acceptable).
Skills
- PyReconstruct
- Python
- R
- Immunohistochemistry
- Fluorescence in situ hybridization
- Super-resolution (dSTORM) microscopy
Location
- AUSTIN, TX
Work Type
- Full-time
Experience Level
- Entry Level
- 1+ years
Education Level
- Bachelor's degree
Salary/Compensations
- $38,000+
Benefits
- Competitive benefits package
About the Company
- Dr. Lyndsey Kirk studies the synaptic basis of age-related cognitive decline and dementia, combining animal behavior, imaging, and molecular biology to understand how synapses change across the aging brain. A core focus of the lab is serial-section electron microscopy-based 3D reconstruction of neural circuits, integrated with behavioral data.
Equal Opportunity
- The University of Texas at Austin, as an equal opportunity/affirmative action employer, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, or veteran status in employment, educational programs and activities, and admissions.
