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About the Role
Lila Sciences is seeking an ML Scientist to advance RNA and DNA sequence design by developing models and strategies for nucleic acid engineering. This role sits at the intersection of machine learning, sequence modeling, and experimental design, focusing on optimizing UTRs, CDS, and regulatory elements to improve sequence-function data generation and analysis.
Responsibilities
- Build ML models for RNA and DNA sequence design across regulatory and coding contexts.
- Develop methods for de novo generation, sequence property prediction, set selection, and active learning.
- Investigate biological mechanisms of designed sequences to refine models and design principles.
- Partner with experimental scientists to propose informative assays and validation strategies.
- Collaborate with cross-functional teams to integrate design models into autonomous platforms.
- Stay current with research in nucleic acid biology and scientific ML, sharing findings externally.
Requirements
- PhD or equivalent experience in machine learning, computational biology, bioengineering, computer science, statistics, or a related quantitative field.
- Hands-on experience building, training, and evaluating ML models for DNA or RNA.
- Strong foundation in modern ML methods.
- Experience developing models for sequence design, sequence-function prediction, generative modeling, or active learning.
- Ability to reason about complex biological systems and formulate ML approaches for sequence-function challenges.
- Curiosity about nucleic acid biology, regulatory genomics, or related fields.
- Strong communication and collaboration skills.
Skills
- PyTorch
- JAX
- Machine Learning
- Computational Biology
- Sequence Modeling
- Generative Modeling
- Active Learning
- RNA Biology
- Regulatory Genomics
Work Type
- Full-time
Experience Level
- I/II
Education Level
- PhD or equivalent
Salary/Compensations
- $176,000—$304,000 USD
Benefits
- Competitive base compensation
- Bonus potential
- Early-stage equity
- Medical, dental, and vision coverage
- Employer-paid life and disability insurance
- Flexible time off
- Paid parental leave
- Educational assistance program
- Commuter benefits
- Company subsidized lunch program
About the Company
- Lila Sciences is building Scientific Superintelligence to solve humankind's greatest challenges.
- The company develops systems that learn for themselves rather than relying on hard-coded expert knowledge.
- LILA combines advanced AI models with proprietary AI Science Factory instruments to execute the scientific method autonomously.
- Core values include truth, trust, curiosity, grit, and velocity.
Equal Opportunity
- Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.