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About the Role

Lead the development and delivery of health economic strategies and evidence to demonstrate the value of innovative therapies and support patient access across the UK and Ireland. This role is critical in shaping market access strategies, developing economic models, and providing expert health economics input for HTA submissions and throughout the product lifecycle, working closely with cross-functional teams and external stakeholders.

Responsibilities

Lead health economics deliverables and inputs into payer evidence generation activities.
Develop and deliver high-quality HTA submissions for UK and Irish agencies.
Provide expert guidance on economic modelling methodologies and evidence generation strategies.
Support pricing, reimbursement, and market access strategies through robust health economic analyses.
Represent the organisation at HTA committee meetings, scientific advice sessions, and other external forums.
Partner with global teams to ensure models and evidence packages meet local market requirements.
Act as a key technical expert and trusted advisor for internal stakeholders.
Develop early-stage cost-effectiveness models to assess access opportunities and identify key value drivers.
Identify evidence gaps and inform data generation strategies.
Support forecasting, pricing, and launch planning through economic analyses.
Contribute to the development of value propositions, budget impact models, and payer-facing tools.
Collaborate with cross-functional teams to identify innovative approaches in health economics and outcomes research.
Lead, oversee, and quality assure the development of cost-effectiveness models, budget impact models, local adaptations, and burden of illness studies.
Develop responses to technical questions from HTA agencies and assessors.
Manage external consultants and vendors delivering health economic projects.
Produce scientific publications, reports, presentations, manuscripts, and conference materials.
Apply advanced quantitative analysis to support value demonstration and commercialization activities.
Build effective relationships with internal and external stakeholders.
Engage confidently with HTA bodies, healthcare decision-makers, and academic experts.
Collaborate with Market Access, Medical Affairs, Government Affairs, and Global Value & Access colleagues to ensure aligned access strategies.
Ensure all activities comply with internal governance, industry regulations, and the ABPI Code of Practice.
Deliver projects on time and within budget.
Maintain high standards of quality assurance across all health economics deliverables.

Requirements

Postgraduate degree (or equivalent experience) in Health Economics, HEOR, Public Health, Economics, or a related discipline.
Minimum 3 years' experience in Health Economics, HEOR, Market Access, or a closely related field.
Experience working within the NHS, pharmaceutical industry, consultancy, or healthcare environment.
Strong knowledge of UK and Ireland HTA processes and methodologies, including NICE, SMC, AWMSG, and NCPE.
Expertise in health economic modelling, cost-effectiveness analysis, and payer evidence generation.
Strong analytical and quantitative skills with the ability to interpret complex datasets.
Demonstrated ability to influence cross-functional stakeholders and operate within complex organisations.
Excellent written, verbal, and presentation skills.
Strong project management and problem-solving capabilities.
Degree in Economics, Life Sciences, Mathematics, Statistics, or related field.
Experience in rare diseases and orphan medicines.
Launch experience within pharmaceutical or biotech environments.
Publications or presentations at recognised HEOR forums (e.g., ISPOR).
Knowledge of advanced evidence synthesis techniques, including indirect treatment comparisons and network meta-analysis.
Experience using modelling and statistical software such as R, SAS, Stata, TreeAge, or similar tools.
Experience applying AI technologies to support health economics modelling or HTA development.

Skills

Health Economics
HEOR
Market Access
Health Economic Modelling
Cost-Effectiveness Analysis
Payer Evidence Generation
Quantitative Analysis
Project Management
Problem-Solving
Written Communication
Verbal Communication
Presentation Skills
Stakeholder Engagement
Data Interpretation
R
SAS
Stata
TreeAge

Location

Pancras Square, London

Work Type

Full-time

Experience Level

Minimum 3 years' experience

Education Level

Postgraduate degree
Degree in Economics, Life Sciences, Mathematics, Statistics, or related field

Salary/Compensations

Competitive salary

Benefits

Competitive benefits

About the Company

AstraZeneca and Alexion focus on bold science to change what is possible for people with serious and uncommon conditions.
They utilize cutting-edge platforms and foster collaboration to unlock new thinking.
The company values kindness alongside ambition, offering high standards with genuine support for employee growth and meaningful outcomes.
Contributions are felt across the business and, importantly, by patients and families.

Equal Opportunity

AstraZeneca and Alexion are committed to building an inclusive and equitable environment where all employees feel they belong.
They welcome and consider applications from all qualified candidates, regardless of characteristics.
Reasonable adjustments/accommodations are offered to help all candidates perform at their best.