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About the Role

We are seeking a highly motivated expert in Organic Electrochemistry, Electrocatalysis, and Microarray Electrosynthesis to actively manipulate organic electrochemical pathways for micro-scale synthetic reactions on high-density arrays. The primary goal is to master the electrochemical environment within our chip architecture to ensure massively parallel and high-fidelity enzymatic DNA synthesis.

Responsibilities

• Serve as the primary subject matter expert in electrochemical synthesis mechanism design on micro-fabricated substrates.
• Engineer the electrocatalytic environment within our chip architecture to ensure highly localized, high-fidelity molecular synthesis.
• Bridge the gap between physical organic reaction mechanisms, redox-mediated pathways, and micro-scale spatial chemical confinement.
• Design and execute high-throughput experimental plans to probe, optimize, and electrochemically confine organic reactions at the micro-electrode interface, minimizing background reactions or active-site crosstalk.
• Develop and optimize novel synthetic organic electrochemical methodologies using potential/current control and redox-mediated pathways to drive chemical transformations within high-density electrode arrays.
• Manipulate electron-transfer kinetics, radical/redox intermediates, overpotentials, and mass transport phenomena at the electrode interface to maximize synthetic yield and current efficiency.
• Partner with protein biochemists, microfluidics experts, surface chemists, and CMOS hardware designers to optimize conditions for enzyme-driven DNA synthesis.
• Document technical breakthroughs through detailed data reporting and present findings to the R&D leadership team.
• Be both a strong individual contributor and a collaborative team member.

Requirements

• Ph.D. in Chemistry with a strong focus on Organic Electrochemistry, Electrocatalysis, or Physical Organic Chemistry.
• Minimum 2 years (Ph.D.) of postgraduate experience in an industrial R&D setting or academic research laboratory, with a proven track record of heavy, hands-on bench contribution.
• Direct, practical experience setting up and executing organic synthetic reactions on microelectrode arrays or functionalized solid supports.
• Deep, intuitive grasp of physical organic chemistry principles, organic reaction mechanisms, and the behavior of redox mediators under potential control.
• Hand-on proficiency with electrochemical characterization (Cyclic Voltammetry, Square Wave Voltammetry) used to elucidate synthesis pathways and investigate intermediate stability.
• Experience managing diffusion, migration, or chemical confinement of reactive intermediates within restricted microfluidic systems or microscale spaces.
• Prior knowledge of DNA synthesis, either phosphoramidite synthesis or enzymatic DNA synthesis.
• Proven ability to translate complex physical organic and electrochemical concepts to hardware engineers and biochemists to achieve shared product goals.
• Must be able to move about the laboratory and office environment regularly, including standing and walking for extended periods (up to 6–8 hours per day).
• Must have fine motor skills and steady hands for handling delicate instruments, operating laboratory equipment, pipetting accurately, and performing repetitive benchwork with precision.
• Must be able to lift and carry up to 40 pounds occasionally.
• Must have sufficient visual acuity for reading small print, instrument displays, and computer monitors, including close vision, color vision, and the ability to adjust focus.
• Must be able to communicate effectively in spoken and written English, including reading technical documents and participating in team meetings.
• Must be able to wear appropriate personal protective equipment (PPE) such as lab coats, gloves, and safety goggles as required.
• Requires frequent standing, sitting, and occasional bending or reaching over lab benches or into biosafety cabinets.

Skills

• Organic Electrochemistry
• Electrocatalysis
• Microarray Electrosynthesis
• Electrochemical synthesis mechanism design
• Microfluidics
• Surface chemistry
• CMOS hardware design
• Electrochemical characterization
• Cyclic Voltammetry
• Square Wave Voltammetry
• Physical organic chemistry
• Organic reaction mechanisms
• Redox mediators
• Electron-transfer kinetics
• Radical/redox intermediates
• Overpotentials
• Mass transport phenomena
• DNA synthesis
• Phosphoramidite synthesis
• Enzymatic DNA synthesis

Work Type

• Bench-intensive
• Execution-focused

Experience Level

• Ph.D. level
• Minimum 2 years postgraduate experience

Education Level

• Ph.D. in Chemistry