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About the Role

The Ramani Lab at Gladstone Institutes is seeking a highly motivated Research Associate to support wet-lab research initiatives. The lab specializes in developing and applying cutting-edge sequencing technologies to investigate transcriptional regulation at a genome-wide scale. Research Associates will help build on recent studies focused on understanding chromatin fiber structure in the contexts of regulated transcription and DNA replication.

Responsibilities

Aiding with lab organization and ordering
Supporting the lab’s biochemistry pipeline for creating and characterizing chromatin in vitro through a combination of protein purification, molecular biology, and genomics data analysis
Generating single-cell and single-molecule sequencing libraries compatible with Illumina and PacBio sequencing platforms
Perform biochemical techniques such as protein purification and in vitro reconstitution of molecular processes
Conduct molecular biology experiments to create sequencing libraries for high-throughput sequencing platforms
Develop and optimize molecular biology protocols, including barcoding, amplification, and processing of DNA and RNA from mammalian cells
Assist with lab organization, including reagent procurement and inventory management
Collaborate with team members to analyze and interpret sequencing data

Requirements

B.S./B.A. degree in a relevant scientific field by the time of hire
Prior experience in protein purification and biochemistry
Candidates currently completing their degree may apply, but the degree must be conferred by the appointment start date

Skills

Molecular biology
Organizational skills
Communication skills
Ability to work independently
High-throughput sequencing technologies
Illumina
Pacific Biosciences
Oxford Nanopore
Molecular biological protocols
Mammalian tissue culture techniques
Bioinformatics
Scripting languages
UNIX
C++
Python
R

Location

Mission Bay, San Francisco

Work Type

Full-time

Experience Level

Research Associate

Education Level

B.S./B.A.

Salary/Compensations

$58,968 - $67,949

Benefits

Competitive salaries
Comprehensive benefits
Generous medical, dental, vision
Retirement plan
Paid vacation
Commuter benefits
Access to free shuttle transportation

About the Company

Gladstone Institutes is a leading independent, not-for-profit research organization dedicated to improving human health through groundbreaking biomedical research and education.
Work spans neuroscience, cardiovascular biology, immunology, and stem cell biology, with a strong emphasis on understanding and treating disease.
Approximately 600 team members, including world-renowned scientists and biomedical leaders.
Fosters a collaborative and innovative environment.
Located at the Mission Bay Campus in a state-of-the-art facility.
Gladstone is an independent state-of-the-art biomedical research institution that empowers its world-class scientists to find new pathways to cures.

Equal Opportunity

Gladstone is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, sex, religion, national origin, ancestry, age, marital status, medical condition, physical or mental disability, veteran status, sexual orientation, or any other non-job related characteristic.
We make all employment decisions so as to further this principle of equal employment.