Impress employers and recruiters.
Choose from hundreds of resume examples.

Impress employers and recruiters.
Choose from hundreds of resume examples.

Target Resume Now

About the Role

Seeking a highly motivated Senior Scientist to join our Protein Expression and Purification group. The successful candidate will play a crucial role in the discovery of novel therapeutics through design and execution of biologics and protein expression activities, primarily focusing on mammalian systems. This role contributes to advancing discovery-stage biologics programs.

Responsibilities

• Design, execute, and optimize recombinant protein expression workflows in mammalian systems (e.g., CHO, HEK293), including transient and stable expression.
• Develop and implement strategies to improve protein yield, quality, and scalability for biologics production.
• Represent the Protein Design and Production group in project team meetings, propose best path forward, contribute to decision making, and coordinate efforts with stakeholders.
• Contribute to DNA construct design, including vector design, cloning strategies, and sequence optimization.
• Work with CRO to coordinate outsourcing production activities.
• Collaborate with cross-functional teams (protein purification, analytics, discovery teams) to deliver high-quality biologics.
• Evaluate and introduce new technologies to enhance efficiency of protein expression platforms.
• Troubleshoot complex expression challenges and propose innovative solutions.
• Maintain accurate documentation of experiments and communicate results effectively to stakeholders.
• Ensure compliance with safety protocols and maintain a clean and organized laboratory environment.
• Collaborate effectively with a group of scientists and demonstrate inclusive behaviors to drive our core mission.

Requirements

• Extensive hands-on experience in recombinant protein and biologics expression in mammalian systems.
• Strong knowledge of cell culture, transfection, process development, and cell line development strategies.
• Solid background in molecular biology, including construct design, cloning, and plasmid engineering.
• Experience working with antibody and complex biologics, bispecifics, fusion proteins.
• Commitment to maintaining accurate and timely records in Electronic Laboratory Notebooks (ELN) and databases.
• Strong problem-solving skills and ability to work in a fast-paced environment.
• Excellent communication and collaboration skills.
• PhD in Molecular Biology, Cell Biology, Biochemistry, or a related discipline with 3+ years of relevant experience (industry preferred); or MS with 4+ years /BS with 7+ years of significant industry experience.
• Consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance.
• Consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance.

Skills

• Cell Cultures
• Cross-Functional Collaboration
• Detail-Oriented
• High-Throughput Screening
• Laboratory Documentation
• Mammalian Cell Culture
• Molecular Biology Techniques
• Primary Cell Culture
• Protein Expression
• Protein Purifications
• Recombinant Protein Expression
• Results-Oriented
• Safety Protocols
• Safety Standards
• Protein production in bioreactors
• Protein purification and characterization techniques
• Bioinformatics tools for sequence analysis and construct design

Location

• South San Francisco

Work Type

• Regular
• Domestic Relocation

Experience Level

• Senior Scientist
• 3+ years of relevant experience (industry preferred)
• 4+ years of relevant experience
• 7+ years of significant industry experience

Education Level

• PhD in Molecular Biology, Cell Biology, Biochemistry, or a related discipline
• MS
• BS

Salary/Compensations

• $131,400.00 - $206,800.00

Benefits

• Annual bonus and long-term incentive, if applicable
• Medical, dental, vision healthcare and other insurance benefits (for employee and family)
• Retirement benefits, including 401(k)
• Paid holidays, vacation, and compassionate and sick days

About the Company

• A global healthcare leader with a diversified portfolio of prescription medicines, vaccines and animal health products.
• The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century.
• Our success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
• We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds.
• The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment.
• We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Equal Opportunity

• Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.
• As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.
• As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.
• For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement
• Learn more about your rights, including under California, Colorado and other US State Acts