About the Role
Xaira Therapeutics is seeking a Principal Associate Scientist for its Biology & Pharmacology team. This hands-on, lab-based role focuses on executing in vitro and ex-vivo experiments to support immunology and translational research programs, ideal for someone with strong experience in immune cell systems and functional assays.
Responsibilities
- Execute in vitro and ex-vivo experiments to support disease biology, target validation, and therapeutic development
- Perform immune cell isolation, culture, and functional assays using primary human and/or mouse systems
- Conduct immune profiling using flow cytometry, including multi-parameter panel execution and analysis
- Perform functional assays such as T cell activation, proliferation, and cytokine profiling
- Prepare and process tissue samples, including generating single-cell suspensions for downstream assays
- Generate, analyze, and clearly document experimental data to support team decision-making
- Maintain accurate lab records and ensure reproducibility of experimental workflows
- Collaborate with cross-functional teams to support ongoing research programs
Requirements
- B.S. or M.S. in Immunology, Biology, or a related field
- 7+ years of relevant industry experience
- Strong hands-on experience with primary immune cell systems (human and/or mouse)
- Proven experience executing flow cytometry-based assays
- Experience with cell-based functional assays (e.g., cytokine assays, proliferation assays)
- Ability to independently execute experiments and troubleshoot technical issues
- Strong attention to detail, organization, and record keeping
- Ability to work effectively in a fast-paced, team-oriented environment
Skills
- Immunology
- Biology
- Drug Discovery
- AI
- Protein Therapeutics
- Antibody Therapeutics
- In vitro experiments
- Ex-vivo experiments
- Immune cell systems
- Functional assays
- Flow cytometry
- Cell-based functional assays
- Cytokine assays
- Proliferation assays
- Tissue sample processing
- Single-cell suspensions
- Data analysis
- Record keeping
Location
- San Francisco Bay Area
- Seattle
- London
Work Type
- Lab-based
- Full-time
Experience Level
- 7+ years of relevant industry experience
Education Level
- B.S. or M.S. in Immunology, Biology, or a related field
Salary/Compensations
- $110,000 to $138,000 annually
Benefits
- Competitive compensation and benefits package
- Open, flexible, and friendly work environment
- Platform to develop long-term careers
- Base salary
- Bonus
- Equity
About the Company
- Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development.
- The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets.
- It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification.
- Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development.
Equal Opportunity
- Xaira Therapeutics an equal-opportunity employer.
- We believe that our strength is in our differences.
- Our goal to build a diverse and inclusive team began on day one, and it will never end.
