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About the Role

As an Applications Scientist, you will support strategic customer collaborations by designing and executing wet lab experiments, generating high-quality nanopore sequencing data, and partnering with bioinformatics, commercial, and R&D teams to deliver meaningful scientific outcomes. This role offers an excellent opportunity to broaden your expertise across diverse sequencing applications while working directly with customers and internal scientific experts.

Responsibilities

Design and execute sequencing experiments, including library preparation strategies and sequencing workflows.
Generate high-quality nanopore sequencing data from diverse sample types.
Perform molecular biology techniques including: DNA and RNA extraction, library preparation, PCR, fragmentation and size selection, library quality control, and cell culture.
Troubleshoot technical challenges related to sample preparation, library construction, multiplexing strategies, and sequencing performance.
Partner with customers and internal teams to support strategic research collaborations.
Provide technical guidance on sequencing workflows, laboratory best practices, expected yields, and read-length optimization.
Collaborate closely with bioinformatics scientists to analyze and interpret sequencing results.
Contribute scientific expertise across multiple nanopore sequencing applications.
Prepare technical reports, presentations, posters, application notes, and other customer-facing materials.
Clearly communicate project outcomes and recommendations to customers and internal stakeholders.
Maintain laboratory inventory, including reagents, consumables, sequencing flow cells, and supplies.
Ensure laboratory activities comply with quality standards, safety procedures, and operational best practices.

Requirements

Bachelor's degree in Molecular Biology, Biochemistry, or a related Life Science discipline with 1–3 years of industry experience, or Master's degree in Molecular Biology, Biochemistry, or a related field.
Strong wet lab molecular biology experience gained through academic or industry research.
Solid understanding of molecular biology principles and experimental design.
Excellent troubleshooting and critical thinking skills.
Strong written and verbal communication abilities.
Ability to manage multiple projects in a collaborative, fast-paced environment.

Skills

Next-generation sequencing (NGS)
Long-read sequencing technologies
Bioinformatics tools
Computational analysis
Linux
Command-line interfaces (CLI)
HPC environments
Python
R
Data analysis workflows
Genomics applications
Transcriptomics
Metagenomics
Targeted sequencing
Whole genome sequencing

Location

Alameda, California

Work Type

Full-time

Experience Level

Early-career scientist
1-3 years of industry experience

Education Level

Bachelor's degree in Molecular Biology, Biochemistry, or a related Life Science discipline
Master's degree in Molecular Biology, Biochemistry, or a related field

Salary/Compensations

$82,400 - $103,000 USD

Benefits

Annual bonus
Stock awards
Healthcare benefits
Company 401(k) plan and company match
Short-term and long-term disability coverage
Basic life insurance
Commuter benefits

About the Company

Oxford Nanopore Technologies (ONT) is transforming the way scientists and researchers analyze DNA and RNA through real-time, accessible sequencing technology.
Our innovative nanopore platform enables breakthroughs across research, clinical genomics, infectious disease, oncology, and many other fields.
Our goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere.
The company has developed a new generation of nanopore-based sensing technology for faster, information rich, accessible and affordable molecular analysis.
The first application is DNA/RNA sequencing, and the technology is in development for the analysis of other types of molecules including proteins.
The technology is used to understand and characterise the biology of humans and diseases such as cancer, plants, animals, bacteria, viruses, and whole environments.
With a thriving culture of ambition and strong innovation goals, Oxford Nanopore is a UK headquartered company with global operations and customers in more than 125 countries.

Equal Opportunity

We are proud to be an equal opportunity employer. We select and employ candidates only in accordance with their merits, qualifications, and abilities to perform the duties of the job regardless of gender, marital status, race, religion, color, age, disability, sexual orientation, military or veteran status.
If you require an accommodation to complete the application or interview process, please contact human.resources@nanoporetech.com
To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf