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About the Role

We are seeking a highly motivated postdoctoral researcher to lead an ambitious project aimed at reconstructing the cell-type-specific connectome of the mouse hypothalamus. You will combine viral tracing, spatial transcriptomics, and computational analysis to uncover how molecularly defined hypothalamic neuronal populations are interconnected to control instinctive behaviours and physiological states.

Responsibilities

• Lead an independent and ambitious research project aligned with the aims outlined above.
• Develop and implement custom viral tracing and spatial transcriptomics workflows, including experimental pipelines, data acquisition, and analysis.
• Generate, analyse, and interpret high-quality datasets
• Establish and maintain close collaborations with computational and experimental researchers within and beyond the institute.
• Scientific and technical support for group members
• Data management and analysis, writing up of manuscripts
• Presenting at scientific meetings
• Guiding PHDs in their research

Requirements

• PhD in Neuroscience or a related field or in the final stages of PhD submission
• Experience with viral tracing, circuit neuroscience, systems neuroscience, or related approaches
• Strong analytical, quantitative, and coding skills (particularly in Python)
• Experience handling and analysing large-scale biological datasets
• Track record of writing papers as evidenced by publications or submitted manuscripts in refereed journals
• Evidence of data presentation at scientific meetings

Skills

• viral tracing
• spatial transcriptomics
• computational analysis
• Python
• data analysis

Location

• UK

Work Type

• full-time
• fixed term (4 years)

Experience Level

• Postdoctoral

Education Level

• PhD

Salary/Compensations

• From £47,500

Benefits

• Sponsorship for UK work visa
• 28 days of annual leave, plus three additional days over Christmas and bank holidays
• Defined contribution pension with employer contributions of up to 16%
• 24/7 GP consultation services
• Occupational health services and mental health support programs
• Eye care vouchers and discounted healthcare plans
• Back-up care for dependents
• Childcare support allowance
• Annual leave purchase options
• Crick Networks offering diverse groups’ support, community and inclusive social events
• Discounted gym memberships
• Bike-to-work scheme
• Shopping discounts
• Subsidised on-site restaurant and social spaces

About the Company

• The Francis Crick Institute is Europe’s largest biomedical research institute under one roof.
• Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.
• The Crick is a place for collaboration, innovation and exploration across many disciplines.
• A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions.
• We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture.
• We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher.
• This gives us the freedom to take risks and carry out high-quality, pioneering research.
• Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.
• The Francis Crick Institute is a biomedical discovery institute researching the biology underlying human health.
• At the Crick, scientists and staff collaborate to stretch the very limits of what we know about how life works.
• Our work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections and neurodegenerative diseases.
• The Francis Crick Institute is a charity, founded by the Medical Research Council, Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

Equal Opportunity

• At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery.
• We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances.
• We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences.
• We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply.
• If you need assistance with applying (i.e., would like to apply by phone or post) please email: karen.au@crick.ac.uk