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About the Role

Join a small, ambitious team from leading institutions like MIT and Harvard Medical School. We seek individuals with speed, rigor, excitement, and a strong work ethic who can bring clarity to open-ended problems, take ownership, and drive projects forward. Capable Labs fosters an environment where high-integrity individuals can dramatically improve, receive close feedback, and earn meaningful scope through contribution.

Responsibilities

Lead therapeutic research programs from conceptualization through early validation in areas such as contraception, stress resilience, cognition, exercise mimetics, recovery, and sleep.
Develop rigorous, scientifically grounded research proposals addressing crucial questions in human health and capability.
Convert research concepts into executable plans by identifying targets, mechanisms, modalities, assay strategies, biomarkers, and establishing clear progression criteria, budgets, and timelines.
Select optimal experimental modalities including RNA, small molecules, peptides, polymers, or biologics-related platforms.
Execute all stages of the research lifecycle: hypothesis development, literature review, experimental design and execution, data analysis, and program evaluation, collaborating closely with scientific colleagues.
Assemble and manage interdisciplinary teams, identify advisors and collaborators, source models and equipment, and oversee research operations.
Maintain direct involvement with experimental data and program strategy.

Requirements

Strong academic record.
Led or significantly contributed to drug discovery or therapeutic programs progressing towards clinical application.
Independently designed and executed scientific research, yielding outcomes such as publications, patents, or funded grants.
Research interests span impactful biomedical topics including sleep, cognition, reproductive health, disease resistance, recovery, aging, and the biological determinants of health.
Demonstrate sound scientific judgment, critically evaluate literature and mechanisms, and define actionable research paths with precision.
Proactive, exacting, analytical, and maintain high scientific standards aligned with academic rigor while advancing projects efficiently and decisively.

Skills

Drug discovery
Therapeutic programs
Scientific research
Publications
Patents
Funded grants
Biomedical research
Sleep research
Cognition research
Reproductive health research
Disease resistance research
Recovery research
Aging research
Health determinants research
Scientific judgment
Literature evaluation
Mechanism evaluation
Research path definition
Experimental design
Data analysis
Program evaluation
RNA modalities
Small molecule modalities
Peptide modalities
Polymer modalities
Biologics-related platforms

Location

San Francisco

Work Type

Onsite
Full-time

Experience Level

Early-stage environment experience
Leadership experience in therapeutic research programs

Education Level

Strong academic record

Salary/Compensations

$180,000-$340,000
Equity options with an implied current value of approximately $50,000-$200,000 before exercise cost, taxes, dilution, and liquidity risk.

Benefits

$500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.
Healthcare: Medical, dental, and vision coverage options with Capable covering 100% of the base policy.
HSA, FSA, and 401K plans.
Healthy dinners with the team are provided daily.
Visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways.

About the Company

Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better.
We believe excellent work should be met with meaningful reward, ownership, and trust.
Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope.

Equal Opportunity

Our process is fast, transparent, and personal. We care about getting to know the person behind the application.
Curious but not sure? Apply anyway. It takes 5 minutes, and you do not need to be actively job searching to start a conversation.
Some of the best people do not map perfectly to a job description. If this sounds like a place where you could do important work, we would like to hear from you.
And if someone exceptional comes to mind, send them our way here. We read every referral carefully, and if your referral joins Capable, we’ll send you a thank-you bonus.