Principal Member of Technical Staff, Full-stack at Edison Scientific | US | Rezi

Principal Member of Technical Staff, Full-stack at Edison Scientific

Principal Member of Technical Staff, Full-stack

Edison Scientific · US

3 weeks ago

Principal Member of Technical Staff, Full-stack

Edison Scientific · US

22 days ago
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About the Role

Edison Scientific is building an AI scientist to accelerate scientific discovery. As a Principal MTS, you will shape and scale our core platform, focusing on backend systems while contributing to user-facing workflows. You will influence architectural direction, establish best practices, and partner with cross-functional teams to deliver end-to-end solutions.

Responsibilities

  • Architect, design, implement, and maintain backend services, APIs, and databases.
  • Drive technical decisions across the stack, balancing scalability, reliability, security, and developer velocity.
  • Lead the design and evolution of data pipelines supporting AI agents and research workflows.
  • Contribute to and review frontend features and workflows, ensuring seamless integration with backend systems.
  • Establish and uphold best practices for testing, monitoring, observability, and incident response.
  • Troubleshoot complex, cross-system issues and guide others through effective debugging and remediation.
  • Collaborate with engineering, design, and research teams to scope, plan, and ship new AI-driven capabilities.
  • Mentor and support other engineers, raising the technical bar and fostering a strong engineering culture.
  • Act as a trusted technical partner in a collaborative team working at the frontier of AI for science.

Requirements

  • Typically, 10+ years of professional software engineering experience, with significant experience across backend systems and full-stack development.
  • Deep proficiency in one or more backend languages (e.g., Python, Node.js), with a strong track record of designing production systems.
  • Extensive experience designing, building, and evolving APIs (FastAPI, REST; GraphQL a plus).
  • Strong working knowledge of modern frontend frameworks (e.g., React, Next.js) and how frontend and backend systems interact at scale.
  • Expertise with relational and/or document databases (PostgreSQL, MySQL, MongoDB, or similar), including schema design and performance considerations.
  • Hands-on experience with cloud infrastructure (AWS, GCP, or Azure) and containerized environments (Docker; Kubernetes preferred).
  • Proven experience building and maintaining CI/CD pipelines, automated testing strategies, and observability systems.
  • Ability to operate autonomously, make sound technical judgments, and drive projects from concept through production.
  • Strong communication skills and experience collaborating across disciplines in fast-moving environments.
  • Experience with data-intensive platforms, scientific computing, or ML/AI infrastructure.
  • Prior experience in startups or small teams with significant architectural ownership and ambiguity.
  • Experience scaling systems, teams, or platforms through periods of rapid growth.

Skills

  • Python
  • Node.js
  • FastAPI
  • REST
  • GraphQL
  • React
  • Next.js
  • PostgreSQL
  • MySQL
  • MongoDB
  • AWS
  • GCP
  • Azure
  • Docker
  • Kubernetes
  • CI/CD
  • Testing
  • Monitoring
  • Observability
  • Incident Response

Location

  • San Francisco

Work Type

  • On-site
  • Full-time

Experience Level

  • Principal
  • 10+ years

Salary/Compensations

  • $200,000 - $350,000
  • Offers equity

Benefits

  • Competitive salary and equity
  • Full healthcare coverage — 100% of premiums paid for employee and dependents
  • Yearly new parent stipend
  • Fertility coverage through Carrot
  • 401(k) company matching
  • $300 health and wellness benefit
  • Daily lunch provided
  • Dinner provided when working late
  • Regular team offsites and company events

About the Company

  • Edison Scientific builds and commercializes AI agents for science.
  • Our mission is to build an AI scientist.
  • We are assembling a team of top researchers and engineers across AI and biology.
  • We operate in a fast-moving, mission-driven culture where smart people do their best work and enjoy it.

Equal Opportunity

  • Edison Scientific is an equal opportunity employer.
  • We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected characteristic under applicable law.