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About the Role

This critical opportunity allows you to apply scientific expertise and strategic analysis to influence high-stakes decisions with direct patient impact. Working at the highest level, you will ensure our choices optimize return on investment and patient outcomes by presenting clear options, tradeoffs, and recommendations tied to value and risk.

Responsibilities

• Own the Oncology R&D portfolio strategy, leading the creation of comprehensive therapeutic area strategies that integrate clinical, scientific, and commercial insights to shape strategic priorities across assets and platforms.
• Advise executive senior leadership by providing disciplined, insight-driven recommendations on complex strategic topics, delivering clear and actionable guidance on portfolio optimization and investment decisions.
• Drive meaningful action by building credibility through expertise, relationships, and trust to persuade and align others without formal authority, leading using robust evidence, metrics, and clear cases to legitimize decisions.
• Partner across the enterprise by collaborating with leaders across clinical development, discovery, business development, and other key functions to create cohesive long-term strategies that drive innovation and impact.
• Set the standards of strong analytical skills to break down complex problems, ensuring decisions, vision, and strategy are firmly grounded in evidence.
• Lead meticulous analysis of internal and external data to identify trends, risks, and opportunities for portfolio growth and optimization, translating findings into actionable strategic recommendations.
• Build and lead a culture of collaboration, innovation, and accountability across all stakeholder groups, partnering with internal and external collaborators to deliver on high-impact strategic objectives.
• Ensure clear and compelling communication of strategy, progress, and priorities to diverse audiences, both internal and external, maintaining transparency and alignment across the organization.
• Integrate clinical trial design, competitive dynamics, regulatory environments, and market access considerations to advise strategic prioritization and investment decisions.
• Drive clarity and consistency across key strategic processes, establishing best practices and maintaining thorough standards for analysis, decision-making, and execution.

Requirements

• BA/BS and 10 years of experience with focus in life science programs, consulting, equity research OR MS/MBA and 8+ years of experience OR PhD or MD and 5+ years of experience
• Deep understanding of Oncology Therapeutic Area Strategy which may include a specific disease area and/or platform technologies, with proven experience contributing to strategic planning and portfolio decisions
• Ability to interact and communicate effectively with senior executive teams, with demonstrated ability to lead and influence experienced professionals in a fast-paced, highly matrixed work environment
• Demonstrates critical and creative thinking, anticipates and solves problems with rigorous, fact-based analysis, and thrives in a fast-paced environment, bringing agility and adaptability to deliver outcomes with clear societal impact.
• PhD in life sciences, MD
• Background in management consulting, venture capital, private equity, or finance with demonstrated ability to conduct rigorous financial and strategic analyses to inform investment and portfolio decisions is strongly preferred
• Experience in strategic planning processes and tools, with ability to translate business needs into coordinated plans and develop creative solutions to complex problems
• Understanding of pharmaceutical R&D business including clinical trial design, drug development processes, regulatory dynamics, and pricing landscapes in major markets
• Strong analytical and communication skills combined with effective interpersonal abilities to build trust, influence without authority, and drive alignment across senior cross-functional teams
• Strong financial background and understanding of forecasts, budgets, and financial tools to support strategic decision-making
• Ability to work across global teams and priorities delivering operational effectiveness and prioritization in a fast-growing, highly matrixed organization

Skills

• Clear and organized thinking
• Ability to simplify and prioritize complex problems
• Strong, data-driven analysis
• Deep scientific acumen
• Ability to establish and maintain credibility with senior audiences
• Proven track record to anticipate and shape the oncology market and key trends with emerging science
• Analytical depth and rigor
• Strategic planning expertise
• Consultative leadership
• Financial acumen

Location

• Office Working Requirements

Work Type

• On average, a minimum of three days per week from the office

Experience Level

• Executive Director

Education Level

• BA/BS
• MS/MBA
• PhD
• MD

Salary/Compensations

• $270,222 to $405,332

Benefits

• Eligibility for various incentives
• Opportunity to receive short-term incentive bonuses
• Equity-based awards for salaried roles
• Commissions for sales roles
• Qualified retirement programs
• Paid time off (i.e., vacation, holiday, and leaves)
• Health, dental, and vision coverage

About the Company

• AstraZeneca is a global, science-led, patient-focused biopharmaceutical company.
• We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases.
• At AstraZeneca, we’re dedicated to being a Great Place to Work.
• Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit.
• To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges.
• There is no better place to make a difference in medicine, patients, and society.
• An inclusive culture where you will connect different thinking to generate new and valuable opportunities.
• Where you will find a commitment to lifelong learning, growth and development for all.
• Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients.
• Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking.
• We’re curious about science and the advancement of knowledge.
• We find creative ways to approach new challenges.
• We’re driven to make the right choices and be accountable for our actions.
• As an organisation centred around what makes us human, we put a big focus on people.
• Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab.
• Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential.
• Here, you’ll do work that has the potential to change your life and improve countless others.
• And, together with your team, you’ll shape a culture that unites and inspires us every day.
• This is your life at AstraZeneca.

Equal Opportunity

• Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees.
• In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics.
• If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.